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Network neighborhood for query Sequence : NDK8_HUMAN

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NDK8_HUMAN
SwissProt Accessions	O60361	Gene names	NME2P1
Domain Architecture
Description	Putative nucleoside diphosphate kinase (EC 2.7.4.6) (NDK) (NDP kinase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NDK8_HUMAN
θ value	1.18825e-76 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O60361	Gene names	NME2P1
Domain Architecture
Description	Putative nucleoside diphosphate kinase (EC 2.7.4.6) (NDK) (NDP kinase).

NDKB_HUMAN
θ value	2.31901e-72 (rank : 2)	NC score	0.998039 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P22392	Gene names	NME2, NM23B
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-H2) (C-myc purine-binding transcription factor PUF).

NDKB_MOUSE
θ value	3.34864e-71 (rank : 3)	NC score	0.997984 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q01768	Gene names	Nme2
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-M2) (P18).

NDKA_MOUSE
θ value	4.68348e-65 (rank : 4)	NC score	0.997097 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P15532	Gene names	Nme1, Nm23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor NM23) (NDPK-A) (nm23-M1).

NDKA_HUMAN
θ value	6.76295e-64 (rank : 5)	NC score	0.996904 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P15531	Gene names	NME1, NDPKA, NM23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor nm23) (nm23-H1) (Granzyme A-activated DNase) (GAAD).

NDK3_HUMAN
θ value	2.18568e-46 (rank : 6)	NC score	0.984385 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13232, Q9BWH4	Gene names	NME3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (DR-nm23).

NDK3_MOUSE
θ value	2.04573e-44 (rank : 7)	NC score	0.983685 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV85, Q9D931, Q9EPA2	Gene names	Nme3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-M3) (DR-nm23).

NDKM_HUMAN
θ value	1.85459e-37 (rank : 8)	NC score	0.972720 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O00746	Gene names	NME4, NM23D
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-H4) (Nucleoside diphosphate kinase D) (NDPKD).

NDKM_MOUSE
θ value	2.67802e-36 (rank : 9)	NC score	0.970922 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV84	Gene names	Nme4
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD).

NDK5_MOUSE
θ value	5.62301e-10 (rank : 10)	NC score	0.679557 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MH5, Q810R1	Gene names	Nme5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-M5).

NDK5_HUMAN
θ value	7.34386e-10 (rank : 11)	NC score	0.692100 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P56597	Gene names	NME5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-H5) (Testis-specific nm23 homolog) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta).

NDK7_MOUSE
θ value	9.59137e-10 (rank : 12)	NC score	0.697954 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

TXND3_HUMAN
θ value	8.11959e-09 (rank : 13)	NC score	0.576223 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

NDK6_HUMAN
θ value	1.06045e-08 (rank : 14)	NC score	0.728138 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O75414, Q96E73, Q9BQ63	Gene names	NME6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-H6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha).

NDK7_HUMAN
θ value	3.08544e-08 (rank : 15)	NC score	0.677288 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B8, Q5TGZ4	Gene names	NME7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).

TXND3_MOUSE
θ value	3.08544e-08 (rank : 16)	NC score	0.561207 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

NDK6_MOUSE
θ value	1.53129e-07 (rank : 17)	NC score	0.715922 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O88425, Q99M53	Gene names	Nme6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-M6).

TXND6_HUMAN
θ value	9.29e-05 (rank : 18)	NC score	0.608584 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

ABCA1_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.005457 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

XRP2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.009979 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O75695, Q86XJ7, Q9NU67	Gene names	RP2
Domain Architecture
Description	Protein XRP2.

Hits sorted by NC score

NDK8_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.18825e-76 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O60361	Gene names	NME2P1
Domain Architecture
Description	Putative nucleoside diphosphate kinase (EC 2.7.4.6) (NDK) (NDP kinase).

NDKB_HUMAN
NC score	0.998039 (rank : 2)	θ value	2.31901e-72 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P22392	Gene names	NME2, NM23B
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-H2) (C-myc purine-binding transcription factor PUF).

NDKB_MOUSE
NC score	0.997984 (rank : 3)	θ value	3.34864e-71 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q01768	Gene names	Nme2
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-M2) (P18).

NDKA_MOUSE
NC score	0.997097 (rank : 4)	θ value	4.68348e-65 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P15532	Gene names	Nme1, Nm23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor NM23) (NDPK-A) (nm23-M1).

NDKA_HUMAN
NC score	0.996904 (rank : 5)	θ value	6.76295e-64 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P15531	Gene names	NME1, NDPKA, NM23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor nm23) (nm23-H1) (Granzyme A-activated DNase) (GAAD).

NDK3_HUMAN
NC score	0.984385 (rank : 6)	θ value	2.18568e-46 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13232, Q9BWH4	Gene names	NME3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (DR-nm23).

NDK3_MOUSE
NC score	0.983685 (rank : 7)	θ value	2.04573e-44 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV85, Q9D931, Q9EPA2	Gene names	Nme3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-M3) (DR-nm23).

NDKM_HUMAN
NC score	0.972720 (rank : 8)	θ value	1.85459e-37 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O00746	Gene names	NME4, NM23D
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-H4) (Nucleoside diphosphate kinase D) (NDPKD).

NDKM_MOUSE
NC score	0.970922 (rank : 9)	θ value	2.67802e-36 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV84	Gene names	Nme4
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD).

NDK6_HUMAN
NC score	0.728138 (rank : 10)	θ value	1.06045e-08 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O75414, Q96E73, Q9BQ63	Gene names	NME6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-H6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha).

NDK6_MOUSE
NC score	0.715922 (rank : 11)	θ value	1.53129e-07 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O88425, Q99M53	Gene names	Nme6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-M6).

NDK7_MOUSE
NC score	0.697954 (rank : 12)	θ value	9.59137e-10 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

NDK5_HUMAN
NC score	0.692100 (rank : 13)	θ value	7.34386e-10 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P56597	Gene names	NME5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-H5) (Testis-specific nm23 homolog) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta).

NDK5_MOUSE
NC score	0.679557 (rank : 14)	θ value	5.62301e-10 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MH5, Q810R1	Gene names	Nme5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-M5).

NDK7_HUMAN
NC score	0.677288 (rank : 15)	θ value	3.08544e-08 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B8, Q5TGZ4	Gene names	NME7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).

TXND6_HUMAN
NC score	0.608584 (rank : 16)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

TXND3_HUMAN
NC score	0.576223 (rank : 17)	θ value	8.11959e-09 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXND3_MOUSE
NC score	0.561207 (rank : 18)	θ value	3.08544e-08 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

XRP2_HUMAN
NC score	0.009979 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O75695, Q86XJ7, Q9NU67	Gene names	RP2
Domain Architecture
Description	Protein XRP2.

ABCA1_HUMAN
NC score	0.005457 (rank : 20)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).