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Network neighborhood for query Sequence : NAMPT_HUMAN

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NAMPT_HUMAN
SwissProt Accessions	P43490, Q3KQV0, Q8WW95	Gene names	NAMPT, PBEF, PBEF1
Domain Architecture
Description	Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Visfatin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NAMPT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P43490, Q3KQV0, Q8WW95	Gene names	NAMPT, PBEF, PBEF1
Domain Architecture
Description	Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Visfatin).

NAMPT_MOUSE
θ value	0 (rank : 2)	NC score	0.997077 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KQ4, Q8C3B5, Q9JKM0	Gene names	Nampt, Pbef1
Domain Architecture	No domain graphic available
Description	Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) (NAmPRTase) (Nampt) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin).

TAU_HUMAN
θ value	0.0961366 (rank : 3)	NC score	0.065591 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	3
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
θ value	0.21417 (rank : 4)	NC score	0.063635 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	502	Shared Neighborhood Hits	3
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CAD23_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.015849 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	5.27518 (rank : 6)	NC score	0.013658 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

KLKB1_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.007111 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

ROBO3_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.007669 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	524	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

GOLP3_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.039694 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4A6, Q9UIW5	Gene names	GOLPH3, GPP34
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 3 (Coat-protein GPP34).

GOLP3_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.039830 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CRA5, Q99KY1, Q9D636	Gene names	Golph3, Gpp34
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 3 (Coat-protein GPP34).

GP176_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.010353 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	522	Shared Neighborhood Hits	4
SwissProt Accessions	Q14439, Q6NXF6	Gene names	GPR176
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (HB-954).

GP176_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.010641 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	539	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

NMDE1_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.005865 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

SYNE1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.003867 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1484	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

Hits sorted by NC score

NAMPT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P43490, Q3KQV0, Q8WW95	Gene names	NAMPT, PBEF, PBEF1
Domain Architecture
Description	Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Visfatin).

NAMPT_MOUSE
NC score	0.997077 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KQ4, Q8C3B5, Q9JKM0	Gene names	Nampt, Pbef1
Domain Architecture	No domain graphic available
Description	Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) (NAmPRTase) (Nampt) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin).

TAU_HUMAN
NC score	0.065591 (rank : 3)	θ value	0.0961366 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	3
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
NC score	0.063635 (rank : 4)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	502	Shared Neighborhood Hits	3
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GOLP3_MOUSE
NC score	0.039830 (rank : 5)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CRA5, Q99KY1, Q9D636	Gene names	Golph3, Gpp34
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 3 (Coat-protein GPP34).

GOLP3_HUMAN
NC score	0.039694 (rank : 6)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4A6, Q9UIW5	Gene names	GOLPH3, GPP34
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 3 (Coat-protein GPP34).

CAD23_HUMAN
NC score	0.015849 (rank : 7)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
NC score	0.013658 (rank : 8)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

GP176_MOUSE
NC score	0.010641 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	539	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

GP176_HUMAN
NC score	0.010353 (rank : 10)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	522	Shared Neighborhood Hits	4
SwissProt Accessions	Q14439, Q6NXF6	Gene names	GPR176
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (HB-954).

ROBO3_MOUSE
NC score	0.007669 (rank : 11)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	524	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

KLKB1_HUMAN
NC score	0.007111 (rank : 12)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

NMDE1_HUMAN
NC score	0.005865 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

SYNE1_HUMAN
NC score	0.003867 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1484	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).