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Network neighborhood for query Sequence : L2GL2_MOUSE

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L2GL2_MOUSE
SwissProt Accessions	Q3TJ91, Q6YP20, Q8K1X0	Gene names	Llgl2, Llglh2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (Lethal giant larvae-like protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

L2GL1_HUMAN
θ value	0 (rank : 1)	NC score	0.978079 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

L2GL1_MOUSE
θ value	0 (rank : 2)	NC score	0.978283 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

L2GL2_HUMAN
θ value	0 (rank : 3)	NC score	0.994096 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P1M3, Q14521, Q9BR62	Gene names	LLGL2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (HGL).

L2GL2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q3TJ91, Q6YP20, Q8K1X0	Gene names	Llgl2, Llglh2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (Lethal giant larvae-like protein 2).

STXB5_MOUSE
θ value	2.23057e-91 (rank : 5)	NC score	0.855572 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STB5L_HUMAN
θ value	3.33315e-87 (rank : 6)	NC score	0.851845 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STXB5_HUMAN
θ value	8.20983e-86 (rank : 7)	NC score	0.850508 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STB5L_MOUSE
θ value	1.07224e-85 (rank : 8)	NC score	0.851226 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

COPB2_HUMAN
θ value	0.00509761 (rank : 9)	NC score	0.094275 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_MOUSE
θ value	0.00509761 (rank : 10)	NC score	0.094305 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

TLE2_HUMAN
θ value	0.0113563 (rank : 11)	NC score	0.118826 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE1_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.119923 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	485	Shared Neighborhood Hits	55
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
θ value	0.0148317 (rank : 13)	NC score	0.119766 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE3_HUMAN
θ value	0.0193708 (rank : 14)	NC score	0.123886 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE3_MOUSE
θ value	0.0193708 (rank : 15)	NC score	0.124097 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	378	Shared Neighborhood Hits	57
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE4_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.118344 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	477	Shared Neighborhood Hits	55
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	0.0193708 (rank : 17)	NC score	0.118276 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	482	Shared Neighborhood Hits	55
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

GEMI5_MOUSE
θ value	0.0736092 (rank : 18)	NC score	0.090348 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	424	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

TLE2_MOUSE
θ value	0.125558 (rank : 19)	NC score	0.111954 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

WD51A_MOUSE
θ value	0.125558 (rank : 20)	NC score	0.091529 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	342	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

COR1C_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.063877 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	246	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

COR1C_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.064046 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

CORO7_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.071531 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	53
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

CORO7_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.075623 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

WDR47_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.067076 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	295	Shared Neighborhood Hits	52
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.067038 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	295	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR53_MOUSE
θ value	0.62314 (rank : 27)	NC score	0.085622 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	254	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

RBBP5_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.117215 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	372	Shared Neighborhood Hits	50
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

WDFY2_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.125391 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDR69_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.065451 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	324	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

TLE6_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.091697 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	178	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

WD51A_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.072966 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

FBW1B_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.059123 (rank : 90)
Query Neighborhood Hits	71	Target Neighborhood Hits	327	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

PRP4_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.058242 (rank : 96)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	54
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

WDFY2_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.122230 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDR49_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.056179 (rank : 108)
Query Neighborhood Hits	71	Target Neighborhood Hits	214	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

WDR61_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.089995 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR61_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.089179 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

AVIL_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.007257 (rank : 156)
Query Neighborhood Hits	71	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O75366	Gene names	AVIL
Domain Architecture
Description	Advillin (p92).

NUP43_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.065048 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

WDR53_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.060847 (rank : 89)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

A16L1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.057260 (rank : 105)
Query Neighborhood Hits	71	Target Neighborhood Hits	776	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

DEK_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.013791 (rank : 150)
Query Neighborhood Hits	71	Target Neighborhood Hits	280	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

PLRG1_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.058936 (rank : 91)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	55
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

TBL1Y_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.078628 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

THOC3_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.061593 (rank : 82)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.061483 (rank : 83)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

WDR35_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.048019 (rank : 144)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WDR7_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.040876 (rank : 147)
Query Neighborhood Hits	71	Target Neighborhood Hits	244	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

APAF_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.066446 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	343	Shared Neighborhood Hits	61
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

BOP1_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.054259 (rank : 124)
Query Neighborhood Hits	71	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

GNB1L_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.131311 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	221	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

K1958_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.012026 (rank : 151)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

TAF5L_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.061849 (rank : 81)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WDR7_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.038406 (rank : 148)
Query Neighborhood Hits	71	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

ATF6A_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.009851 (rank : 152)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

BRCA1_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.005761 (rank : 157)
Query Neighborhood Hits	71	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CTR9_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.009776 (rank : 153)
Query Neighborhood Hits	71	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

PLRG1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.057115 (rank : 107)
Query Neighborhood Hits	71	Target Neighborhood Hits	318	Shared Neighborhood Hits	55
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PRP4_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.057206 (rank : 106)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PWP2_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.046540 (rank : 145)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

TAF5_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.058089 (rank : 99)
Query Neighborhood Hits	71	Target Neighborhood Hits	352	Shared Neighborhood Hits	56
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.058190 (rank : 97)
Query Neighborhood Hits	71	Target Neighborhood Hits	366	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

CTR9_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.009318 (rank : 155)
Query Neighborhood Hits	71	Target Neighborhood Hits	383	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

DAXX_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.018754 (rank : 149)
Query Neighborhood Hits	71	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

EMAL2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.044422 (rank : 146)
Query Neighborhood Hits	71	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

GNB1L_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.102026 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

PAG1_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.009694 (rank : 154)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

TBLX_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.076048 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

WDR57_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.067205 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WDR57_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.067285 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

A16L1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.051548 (rank : 140)
Query Neighborhood Hits	71	Target Neighborhood Hits	664	Shared Neighborhood Hits	57
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

AAMP_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.074210 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	59
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

AES_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.080437 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q08117, Q12808, Q96TG9, Q9UDY9	Gene names	AES, GRG
Domain Architecture
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Gp130-associated protein GAM).

AES_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.080495 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P63002, Q06195	Gene names	Aes, Esp1, Grg
Domain Architecture	No domain graphic available
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Grg-5).

APAF_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.054070 (rank : 126)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

DDB2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.058687 (rank : 92)
Query Neighborhood Hits	71	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

DDB2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.062929 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

DMWD_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.054529 (rank : 120)
Query Neighborhood Hits	71	Target Neighborhood Hits	282	Shared Neighborhood Hits	49
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DNAI2_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.066996 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	156	Shared Neighborhood Hits	32
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

FBW1A_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.058613 (rank : 93)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

GBB5_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.052578 (rank : 132)
Query Neighborhood Hits	71	Target Neighborhood Hits	299	Shared Neighborhood Hits	56
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB5_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.052474 (rank : 135)
Query Neighborhood Hits	71	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBLP_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.061314 (rank : 86)
Query Neighborhood Hits	71	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.061314 (rank : 87)
Query Neighborhood Hits	71	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

GEMI5_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.080172 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	362	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

KTNB1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.072877 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	349	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.072846 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	356	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

LIS1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.050236 (rank : 142)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	54
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.050229 (rank : 143)
Query Neighborhood Hits	71	Target Neighborhood Hits	336	Shared Neighborhood Hits	54
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

MEP50_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.052803 (rank : 131)
Query Neighborhood Hits	71	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

MEP50_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.067373 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	271	Shared Neighborhood Hits	56
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

NEDD1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.068079 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

NEDD1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.055272 (rank : 115)
Query Neighborhood Hits	71	Target Neighborhood Hits	281	Shared Neighborhood Hits	50
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

NLE1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.070149 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

NLE1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.071204 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

NUP43_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.061307 (rank : 88)
Query Neighborhood Hits	71	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

PK1IP_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.088201 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	277	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

PK1IP_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.085739 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

PRP19_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.055273 (rank : 114)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

PRP19_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.053039 (rank : 130)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	55
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

PWP1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.052522 (rank : 133)
Query Neighborhood Hits	71	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

RAE1L_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.051961 (rank : 138)
Query Neighborhood Hits	71	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RAE1L_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.052490 (rank : 134)
Query Neighborhood Hits	71	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RBBP4_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.058147 (rank : 98)
Query Neighborhood Hits	71	Target Neighborhood Hits	291	Shared Neighborhood Hits	54
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.058576 (rank : 94)
Query Neighborhood Hits	71	Target Neighborhood Hits	289	Shared Neighborhood Hits	53
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP7_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.057497 (rank : 101)
Query Neighborhood Hits	71	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.057459 (rank : 102)
Query Neighborhood Hits	71	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

SMU1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.070833 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.070833 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SPG16_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.062437 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	361	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SPG16_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.076004 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	377	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

STRN3_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.054415 (rank : 123)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN4_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.054499 (rank : 121)
Query Neighborhood Hits	71	Target Neighborhood Hits	325	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

STRN4_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.057831 (rank : 100)
Query Neighborhood Hits	71	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

STXB6_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.133517 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFX7, Q8N3H1, Q8N8D5, Q96GF3, Q9P008	Gene names	STXBP6
Domain Architecture
Description	Syntaxin-binding protein 6 (Amisyn).

STXB6_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.138533 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3T5	Gene names	Stxbp6
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 6.

TAF5L_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.054134 (rank : 125)
Query Neighborhood Hits	71	Target Neighborhood Hits	330	Shared Neighborhood Hits	55
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TBL1R_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.069275 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	327	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.069226 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1X_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.076222 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TEP1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.076100 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	371	Shared Neighborhood Hits	60
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

TEP1_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.068020 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

TF3C2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.057410 (rank : 103)
Query Neighborhood Hits	71	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TF3C2_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.055766 (rank : 112)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

THOC6_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.050645 (rank : 141)
Query Neighborhood Hits	71	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TLE6_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.084155 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	120	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

U3IP2_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.061448 (rank : 84)
Query Neighborhood Hits	71	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

U3IP2_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.061324 (rank : 85)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	55
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

UTP15_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.051777 (rank : 139)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

UTP15_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.064992 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

UTP18_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.054807 (rank : 119)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WD51B_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.055961 (rank : 110)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WD51B_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.057354 (rank : 104)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDFY1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.086231 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	305	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDR12_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.063726 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	300	Shared Neighborhood Hits	55
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR12_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.064370 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	301	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR16_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.052469 (rank : 136)
Query Neighborhood Hits	71	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR16_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.056104 (rank : 109)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

WDR17_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.071282 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

WDR20_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.055748 (rank : 113)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

WDR23_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.063881 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

WDR23_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.063799 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	271	Shared Neighborhood Hits	53
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

WDR24_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.066199 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR24_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.066977 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR31_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.058466 (rank : 95)
Query Neighborhood Hits	71	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

WDR33_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052173 (rank : 137)
Query Neighborhood Hits	71	Target Neighborhood Hits	638	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

WDR36_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.075686 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

WDR3_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.075896 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

WDR54_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.055869 (rank : 111)
Query Neighborhood Hits	71	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR55_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.053576 (rank : 127)
Query Neighborhood Hits	71	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR5_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055245 (rank : 116)
Query Neighborhood Hits	71	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.055245 (rank : 117)
Query Neighborhood Hits	71	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WSB1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.055013 (rank : 118)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WSB1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.053161 (rank : 129)
Query Neighborhood Hits	71	Target Neighborhood Hits	313	Shared Neighborhood Hits	53
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

WSB2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.053448 (rank : 128)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

WSB2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.054437 (rank : 122)
Query Neighborhood Hits	71	Target Neighborhood Hits	306	Shared Neighborhood Hits	54
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

Hits sorted by NC score

L2GL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q3TJ91, Q6YP20, Q8K1X0	Gene names	Llgl2, Llglh2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (Lethal giant larvae-like protein 2).

L2GL2_HUMAN
NC score	0.994096 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P1M3, Q14521, Q9BR62	Gene names	LLGL2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (HGL).

L2GL1_MOUSE
NC score	0.978283 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

L2GL1_HUMAN
NC score	0.978079 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

STXB5_MOUSE
NC score	0.855572 (rank : 5)	θ value	2.23057e-91 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STB5L_HUMAN
NC score	0.851845 (rank : 6)	θ value	3.33315e-87 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_MOUSE
NC score	0.851226 (rank : 7)	θ value	1.07224e-85 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STXB5_HUMAN
NC score	0.850508 (rank : 8)	θ value	8.20983e-86 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB6_MOUSE
NC score	0.138533 (rank : 9)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3T5	Gene names	Stxbp6
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 6.

STXB6_HUMAN
NC score	0.133517 (rank : 10)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFX7, Q8N3H1, Q8N8D5, Q96GF3, Q9P008	Gene names	STXBP6
Domain Architecture
Description	Syntaxin-binding protein 6 (Amisyn).

GNB1L_HUMAN
NC score	0.131311 (rank : 11)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	221	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

WDFY2_HUMAN
NC score	0.125391 (rank : 12)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

TLE3_MOUSE
NC score	0.124097 (rank : 13)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	378	Shared Neighborhood Hits	57
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE3_HUMAN
NC score	0.123886 (rank : 14)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

WDFY2_MOUSE
NC score	0.122230 (rank : 15)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

TLE1_HUMAN
NC score	0.119923 (rank : 16)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	485	Shared Neighborhood Hits	55
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
NC score	0.119766 (rank : 17)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE2_HUMAN
NC score	0.118826 (rank : 18)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE4_HUMAN
NC score	0.118344 (rank : 19)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	477	Shared Neighborhood Hits	55
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
NC score	0.118276 (rank : 20)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	482	Shared Neighborhood Hits	55
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

RBBP5_HUMAN
NC score	0.117215 (rank : 21)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	372	Shared Neighborhood Hits	50
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

TLE2_MOUSE
NC score	0.111954 (rank : 22)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

GNB1L_MOUSE
NC score	0.102026 (rank : 23)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

COPB2_MOUSE
NC score	0.094305 (rank : 24)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_HUMAN
NC score	0.094275 (rank : 25)	θ value	0.00509761 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

TLE6_MOUSE
NC score	0.091697 (rank : 26)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	178	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

WD51A_MOUSE
NC score	0.091529 (rank : 27)	θ value	0.125558 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	342	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

GEMI5_MOUSE
NC score	0.090348 (rank : 28)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	424	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

WDR61_HUMAN
NC score	0.089995 (rank : 29)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR61_MOUSE
NC score	0.089179 (rank : 30)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

PK1IP_HUMAN
NC score	0.088201 (rank : 31)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	71	Target Neighborhood Hits	277	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

WDFY1_HUMAN
NC score	0.086231 (rank : 32)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	71	Target Neighborhood Hits	305	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

PK1IP_MOUSE
NC score	0.085739 (rank : 33)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	71	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

WDR53_MOUSE
NC score	0.085622 (rank : 34)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	254	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

TLE6_HUMAN
NC score	0.084155 (rank : 35)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	71	Target Neighborhood Hits	120	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

AES_MOUSE
NC score	0.080495 (rank : 36)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P63002, Q06195	Gene names	Aes, Esp1, Grg
Domain Architecture	No domain graphic available
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Grg-5).

AES_HUMAN
NC score	0.080437 (rank : 37)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q08117, Q12808, Q96TG9, Q9UDY9	Gene names	AES, GRG
Domain Architecture
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Gp130-associated protein GAM).

GEMI5_HUMAN
NC score	0.080172 (rank : 38)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	71	Target Neighborhood Hits	362	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

TBL1Y_HUMAN
NC score	0.078628 (rank : 39)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TBL1X_HUMAN
NC score	0.076222 (rank : 40)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TEP1_HUMAN
NC score	0.076100 (rank : 41)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	71	Target Neighborhood Hits	371	Shared Neighborhood Hits	60
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

TBLX_MOUSE
NC score	0.076048 (rank : 42)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

SPG16_MOUSE
NC score	0.076004 (rank : 43)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	71	Target Neighborhood Hits	377	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WDR3_HUMAN
NC score	0.075896 (rank : 44)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

WDR36_HUMAN
NC score	0.075686 (rank : 45)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

CORO7_MOUSE
NC score	0.075623 (rank : 46)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

AAMP_HUMAN
NC score	0.074210 (rank : 47)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	59
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

WD51A_HUMAN
NC score	0.072966 (rank : 48)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

KTNB1_HUMAN
NC score	0.072877 (rank : 49)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	71	Target Neighborhood Hits	349	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
NC score	0.072846 (rank : 50)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	71	Target Neighborhood Hits	356	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

CORO7_HUMAN
NC score	0.071531 (rank : 51)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	315	Shared Neighborhood Hits	53
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

WDR17_HUMAN
NC score	0.071282 (rank : 52)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

NLE1_MOUSE
NC score	0.071204 (rank : 53)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

SMU1_HUMAN
NC score	0.070833 (rank : 54)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	71	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
NC score	0.070833 (rank : 55)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	71	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

NLE1_HUMAN
NC score	0.070149 (rank : 56)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

TBL1R_HUMAN
NC score	0.069275 (rank : 57)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	71	Target Neighborhood Hits	327	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
NC score	0.069226 (rank : 58)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

NEDD1_HUMAN
NC score	0.068079 (rank : 59)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

TEP1_MOUSE
NC score	0.068020 (rank : 60)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

MEP50_MOUSE
NC score	0.067373 (rank : 61)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	71	Target Neighborhood Hits	271	Shared Neighborhood Hits	56
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR57_MOUSE
NC score	0.067285 (rank : 62)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

WDR57_HUMAN
NC score	0.067205 (rank : 63)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WDR47_HUMAN
NC score	0.067076 (rank : 64)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	295	Shared Neighborhood Hits	52
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_MOUSE
NC score	0.067038 (rank : 65)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	295	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

DNAI2_HUMAN
NC score	0.066996 (rank : 66)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	156	Shared Neighborhood Hits	32
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

WDR24_MOUSE
NC score	0.066977 (rank : 67)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

APAF_MOUSE
NC score	0.066446 (rank : 68)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	343	Shared Neighborhood Hits	61
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR24_HUMAN
NC score	0.066199 (rank : 69)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	71	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR69_HUMAN
NC score	0.065451 (rank : 70)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	324	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

NUP43_HUMAN
NC score	0.065048 (rank : 71)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

UTP15_MOUSE
NC score	0.064992 (rank : 72)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

WDR12_MOUSE
NC score	0.064370 (rank : 73)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	71	Target Neighborhood Hits	301	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

COR1C_MOUSE
NC score	0.064046 (rank : 74)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

WDR23_HUMAN
NC score	0.063881 (rank : 75)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	71	Target Neighborhood Hits	267	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

COR1C_HUMAN
NC score	0.063877 (rank : 76)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	246	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

WDR23_MOUSE
NC score	0.063799 (rank : 77)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	71	Target Neighborhood Hits	271	Shared Neighborhood Hits	53
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

WDR12_HUMAN
NC score	0.063726 (rank : 78)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	71	Target Neighborhood Hits	300	Shared Neighborhood Hits	55
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

DDB2_MOUSE
NC score	0.062929 (rank : 79)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

SPG16_HUMAN
NC score	0.062437 (rank : 80)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	71	Target Neighborhood Hits	361	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

TAF5L_MOUSE
NC score	0.061849 (rank : 81)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

THOC3_HUMAN
NC score	0.061593 (rank : 82)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
NC score	0.061483 (rank : 83)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

U3IP2_HUMAN
NC score	0.061448 (rank : 84)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	71	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

U3IP2_MOUSE
NC score	0.061324 (rank : 85)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	55
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

GBLP_HUMAN
NC score	0.061314 (rank : 86)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	71	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
NC score	0.061314 (rank : 87)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	71	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

NUP43_MOUSE
NC score	0.061307 (rank : 88)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	71	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

WDR53_HUMAN
NC score	0.060847 (rank : 89)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

FBW1B_HUMAN
NC score	0.059123 (rank : 90)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	327	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

PLRG1_MOUSE
NC score	0.058936 (rank : 91)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	55
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

DDB2_HUMAN
NC score	0.058687 (rank : 92)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

FBW1A_HUMAN
NC score	0.058613 (rank : 93)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

RBBP4_MOUSE
NC score	0.058576 (rank : 94)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	71	Target Neighborhood Hits	289	Shared Neighborhood Hits	53
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

WDR31_MOUSE
NC score	0.058466 (rank : 95)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	71	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

PRP4_HUMAN
NC score	0.058242 (rank : 96)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	54
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

TAF5_MOUSE
NC score	0.058190 (rank : 97)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	366	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

RBBP4_HUMAN
NC score	0.058147 (rank : 98)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	71	Target Neighborhood Hits	291	Shared Neighborhood Hits	54
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

TAF5_HUMAN
NC score	0.058089 (rank : 99)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	352	Shared Neighborhood Hits	56
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

STRN4_MOUSE
NC score	0.057831 (rank : 100)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	71	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

RBBP7_HUMAN
NC score	0.057497 (rank : 101)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	71	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
NC score	0.057459 (rank : 102)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	71	Target Neighborhood Hits	285	Shared Neighborhood Hits	55
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

TF3C2_HUMAN
NC score	0.057410 (rank : 103)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	71	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WD51B_MOUSE
NC score	0.057354 (rank : 104)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

A16L1_MOUSE
NC score	0.057260 (rank : 105)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	776	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

PRP4_MOUSE
NC score	0.057206 (rank : 106)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PLRG1_HUMAN
NC score	0.057115 (rank : 107)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	318	Shared Neighborhood Hits	55
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR49_HUMAN
NC score	0.056179 (rank : 108)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	214	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

WDR16_MOUSE
NC score	0.056104 (rank : 109)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

WD51B_HUMAN
NC score	0.055961 (rank : 110)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR54_MOUSE
NC score	0.055869 (rank : 111)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	71	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

TF3C2_MOUSE
NC score	0.055766 (rank : 112)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WDR20_HUMAN
NC score	0.055748 (rank : 113)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

PRP19_HUMAN
NC score	0.055273 (rank : 114)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

NEDD1_MOUSE
NC score	0.055272 (rank : 115)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	71	Target Neighborhood Hits	281	Shared Neighborhood Hits	50
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

WDR5_HUMAN
NC score	0.055245 (rank : 116)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	71	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.055245 (rank : 117)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	71	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WSB1_HUMAN
NC score	0.055013 (rank : 118)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

UTP18_HUMAN
NC score	0.054807 (rank : 119)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

DMWD_MOUSE
NC score	0.054529 (rank : 120)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	282	Shared Neighborhood Hits	49
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

STRN4_HUMAN
NC score	0.054499 (rank : 121)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	71	Target Neighborhood Hits	325	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

WSB2_MOUSE
NC score	0.054437 (rank : 122)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	71	Target Neighborhood Hits	306	Shared Neighborhood Hits	54
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

STRN3_MOUSE
NC score	0.054415 (rank : 123)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

BOP1_MOUSE
NC score	0.054259 (rank : 124)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

TAF5L_HUMAN
NC score	0.054134 (rank : 125)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	71	Target Neighborhood Hits	330	Shared Neighborhood Hits	55
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

APAF_HUMAN
NC score	0.054070 (rank : 126)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	334	Shared Neighborhood Hits	60
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR55_MOUSE
NC score	0.053576 (rank : 127)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	71	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WSB2_HUMAN
NC score	0.053448 (rank : 128)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	71	Target Neighborhood Hits	308	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

WSB1_MOUSE
NC score	0.053161 (rank : 129)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	71	Target Neighborhood Hits	313	Shared Neighborhood Hits	53
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

PRP19_MOUSE
NC score	0.053039 (rank : 130)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	71	Target Neighborhood Hits	335	Shared Neighborhood Hits	55
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

MEP50_HUMAN
NC score	0.052803 (rank : 131)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	71	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

GBB5_HUMAN
NC score	0.052578 (rank : 132)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	71	Target Neighborhood Hits	299	Shared Neighborhood Hits	56
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

PWP1_MOUSE
NC score	0.052522 (rank : 133)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	71	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

RAE1L_MOUSE
NC score	0.052490 (rank : 134)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	71	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

GBB5_MOUSE
NC score	0.052474 (rank : 135)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	71	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

WDR16_HUMAN
NC score	0.052469 (rank : 136)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	71	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR33_HUMAN
NC score	0.052173 (rank : 137)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	71	Target Neighborhood Hits	638	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

RAE1L_HUMAN
NC score	0.051961 (rank : 138)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	71	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

UTP15_HUMAN
NC score	0.051777 (rank : 139)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

A16L1_HUMAN
NC score	0.051548 (rank : 140)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	664	Shared Neighborhood Hits	57
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

THOC6_HUMAN
NC score	0.050645 (rank : 141)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	71	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

LIS1_HUMAN
NC score	0.050236 (rank : 142)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	54
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
NC score	0.050229 (rank : 143)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	71	Target Neighborhood Hits	336	Shared Neighborhood Hits	54
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WDR35_HUMAN
NC score	0.048019 (rank : 144)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

PWP2_MOUSE
NC score	0.046540 (rank : 145)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	309	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

EMAL2_HUMAN
NC score	0.044422 (rank : 146)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

WDR7_HUMAN
NC score	0.040876 (rank : 147)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	244	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

WDR7_MOUSE
NC score	0.038406 (rank : 148)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

DAXX_HUMAN
NC score	0.018754 (rank : 149)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DEK_MOUSE
NC score	0.013791 (rank : 150)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	280	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

K1958_MOUSE
NC score	0.012026 (rank : 151)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

ATF6A_HUMAN
NC score	0.009851 (rank : 152)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CTR9_MOUSE
NC score	0.009776 (rank : 153)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

PAG1_MOUSE
NC score	0.009694 (rank : 154)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

CTR9_HUMAN
NC score	0.009318 (rank : 155)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	383	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

AVIL_HUMAN
NC score	0.007257 (rank : 156)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O75366	Gene names	AVIL
Domain Architecture
Description	Advillin (p92).

BRCA1_HUMAN
NC score	0.005761 (rank : 157)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).