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Network neighborhood for query Sequence : KU86_HUMAN

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KU86_HUMAN
SwissProt Accessions	P13010, Q4VBQ5, Q9UCQ0, Q9UCQ1	Gene names	XRCC5, G22P2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Lupus Ku autoantigen protein p86) (Ku86) (Ku80) (86 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KU86_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P13010, Q4VBQ5, Q9UCQ0, Q9UCQ1	Gene names	XRCC5, G22P2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Lupus Ku autoantigen protein p86) (Ku86) (Ku80) (86 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

KU86_MOUSE
θ value	0 (rank : 2)	NC score	0.990401 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P27641	Gene names	Xrcc5, G22p2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Ku autoantigen protein p86 homolog) (Ku80) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

TPX2_HUMAN
θ value	0.365318 (rank : 3)	NC score	0.069443 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

DREB_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.037890 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	446	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

BAZ1B_MOUSE
θ value	1.06291 (rank : 5)	NC score	0.039966 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

PGS1_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.011477 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	265	Shared Neighborhood Hits	2
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

TF3C4_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.066726 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

BAZ1B_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.033055 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	701	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

KTN1_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.008974 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	1197	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TF3C4_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.056291 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

RPGF6_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.014850 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

LBN_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.016591 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LPHN1_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.012072 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

ANR12_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.004702 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	1081	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

MTM1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.007100 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

NUP54_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.014799 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

Hits sorted by NC score

KU86_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P13010, Q4VBQ5, Q9UCQ0, Q9UCQ1	Gene names	XRCC5, G22P2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Lupus Ku autoantigen protein p86) (Ku86) (Ku80) (86 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

KU86_MOUSE
NC score	0.990401 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P27641	Gene names	Xrcc5, G22p2
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Ku autoantigen protein p86 homolog) (Ku80) (CTC box-binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5).

TPX2_HUMAN
NC score	0.069443 (rank : 3)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TF3C4_HUMAN
NC score	0.066726 (rank : 4)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

TF3C4_MOUSE
NC score	0.056291 (rank : 5)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

BAZ1B_MOUSE
NC score	0.039966 (rank : 6)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

DREB_MOUSE
NC score	0.037890 (rank : 7)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	446	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

BAZ1B_HUMAN
NC score	0.033055 (rank : 8)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	701	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

LBN_MOUSE
NC score	0.016591 (rank : 9)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

RPGF6_HUMAN
NC score	0.014850 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

NUP54_MOUSE
NC score	0.014799 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

LPHN1_HUMAN
NC score	0.012072 (rank : 12)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

PGS1_MOUSE
NC score	0.011477 (rank : 13)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	265	Shared Neighborhood Hits	2
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

KTN1_HUMAN
NC score	0.008974 (rank : 14)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	1197	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MTM1_HUMAN
NC score	0.007100 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

ANR12_HUMAN
NC score	0.004702 (rank : 16)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	1081	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).