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Network neighborhood for query Sequence : IGF1B_HUMAN

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IGF1B_HUMAN
SwissProt Accessions	P05019	Gene names	IGF1, IBP1
Domain Architecture
Description	Insulin-like growth factor IB precursor (IGF-IB) (Somatomedin C) (Mechano growth factor) (MGF).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IGF1B_HUMAN
θ value	4.1775e-114 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P05019	Gene names	IGF1, IBP1
Domain Architecture
Description	Insulin-like growth factor IB precursor (IGF-IB) (Somatomedin C) (Mechano growth factor) (MGF).

IGF1A_HUMAN
θ value	7.70199e-76 (rank : 2)	NC score	0.994053 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01343	Gene names	IGF1, IBP1
Domain Architecture
Description	Insulin-like growth factor IA precursor (IGF-IA) (Somatomedin C) (Mechano growth factor) (MGF).

IGF1_MOUSE
θ value	8.24801e-70 (rank : 3)	NC score	0.992251 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P05017, P05018, Q6LDP4, Q8C4U6	Gene names	Igf1, Igf-1
Domain Architecture
Description	Insulin-like growth factor I precursor (IGF-I) (Somatomedin).

IGF2_HUMAN
θ value	5.07402e-19 (rank : 4)	NC score	0.814980 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P01344, P78449, Q14299, Q9UC68, Q9UC69	Gene names	IGF2
Domain Architecture
Description	Insulin-like growth factor II precursor (IGF-II) (Somatomedin A) [Contains: Insulin-like growth factor II Ala-25 Del].

IGF2_MOUSE
θ value	5.07402e-19 (rank : 5)	NC score	0.815812 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P09535	Gene names	Igf2, Igf-2
Domain Architecture
Description	Insulin-like growth factor II precursor (Multiplication-stimulating polypeptide) (IGF-II).

INS_HUMAN
θ value	1.09739e-05 (rank : 6)	NC score	0.529992 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P01308	Gene names	INS
Domain Architecture
Description	Insulin precursor [Contains: Insulin B chain; Insulin A chain].

INS2_MOUSE
θ value	3.19293e-05 (rank : 7)	NC score	0.509904 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01326	Gene names	Ins2, Ins-2
Domain Architecture
Description	Insulin-2 precursor [Contains: Insulin-2 B chain; Insulin-2 A chain].

INS1_MOUSE
θ value	5.44631e-05 (rank : 8)	NC score	0.506146 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P01325, Q9D907	Gene names	Ins1, Ins-1
Domain Architecture
Description	Insulin-1 precursor [Contains: Insulin-1 B chain; Insulin-1 A chain].

NCOR2_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.024878 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PITX2_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.011191 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	383	Shared Neighborhood Hits	2
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

CD83_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.023528 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q01151	Gene names	CD83
Domain Architecture
Description	CD83 antigen precursor (Cell surface protein HB15) (B-cell activation protein).

Hits sorted by NC score

IGF1B_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.1775e-114 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P05019	Gene names	IGF1, IBP1
Domain Architecture
Description	Insulin-like growth factor IB precursor (IGF-IB) (Somatomedin C) (Mechano growth factor) (MGF).

IGF1A_HUMAN
NC score	0.994053 (rank : 2)	θ value	7.70199e-76 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01343	Gene names	IGF1, IBP1
Domain Architecture
Description	Insulin-like growth factor IA precursor (IGF-IA) (Somatomedin C) (Mechano growth factor) (MGF).

IGF1_MOUSE
NC score	0.992251 (rank : 3)	θ value	8.24801e-70 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P05017, P05018, Q6LDP4, Q8C4U6	Gene names	Igf1, Igf-1
Domain Architecture
Description	Insulin-like growth factor I precursor (IGF-I) (Somatomedin).

IGF2_MOUSE
NC score	0.815812 (rank : 4)	θ value	5.07402e-19 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P09535	Gene names	Igf2, Igf-2
Domain Architecture
Description	Insulin-like growth factor II precursor (Multiplication-stimulating polypeptide) (IGF-II).

IGF2_HUMAN
NC score	0.814980 (rank : 5)	θ value	5.07402e-19 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P01344, P78449, Q14299, Q9UC68, Q9UC69	Gene names	IGF2
Domain Architecture
Description	Insulin-like growth factor II precursor (IGF-II) (Somatomedin A) [Contains: Insulin-like growth factor II Ala-25 Del].

INS_HUMAN
NC score	0.529992 (rank : 6)	θ value	1.09739e-05 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P01308	Gene names	INS
Domain Architecture
Description	Insulin precursor [Contains: Insulin B chain; Insulin A chain].

INS2_MOUSE
NC score	0.509904 (rank : 7)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P01326	Gene names	Ins2, Ins-2
Domain Architecture
Description	Insulin-2 precursor [Contains: Insulin-2 B chain; Insulin-2 A chain].

INS1_MOUSE
NC score	0.506146 (rank : 8)	θ value	5.44631e-05 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P01325, Q9D907	Gene names	Ins1, Ins-1
Domain Architecture
Description	Insulin-1 precursor [Contains: Insulin-1 B chain; Insulin-1 A chain].

NCOR2_HUMAN
NC score	0.024878 (rank : 10)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CD83_HUMAN
NC score	0.023528 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q01151	Gene names	CD83
Domain Architecture
Description	CD83 antigen precursor (Cell surface protein HB15) (B-cell activation protein).

PITX2_MOUSE
NC score	0.011191 (rank : 12)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	383	Shared Neighborhood Hits	2
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).