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Network neighborhood for query Sequence : ICMT_HUMAN

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ICMT_HUMAN
SwissProt Accessions	O60725	Gene names	ICMT, PCCMT
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ICMT_HUMAN
θ value	8.0589e-150 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O60725	Gene names	ICMT, PCCMT
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

ICMT_MOUSE
θ value	4.90052e-139 (rank : 2)	NC score	0.999583 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQK7	Gene names	Icmt
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

ERG24_HUMAN
θ value	4.03905 (rank : 3)	NC score	0.030019 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O76062, O95982, Q8IY06, Q96E64, Q96GZ1	Gene names	TM7SF2, ANG1
Domain Architecture
Description	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Delta14-SR) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR- 1).

GPR45_HUMAN
θ value	6.88961 (rank : 4)	NC score	0.006016 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Y3, Q6NWS4	Gene names	GPR45
Domain Architecture
Description	Probable G-protein coupled receptor 45 (PSP24-alpha) (PSP24-1).

GPR45_MOUSE
θ value	8.99809 (rank : 5)	NC score	0.005552 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	742	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ4	Gene names	Gpr45
Domain Architecture
Description	Probable G-protein coupled receptor 45 (PSP24-alpha) (PSP24-1).

Hits sorted by NC score

ICMT_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.0589e-150 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O60725	Gene names	ICMT, PCCMT
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

ICMT_MOUSE
NC score	0.999583 (rank : 2)	θ value	4.90052e-139 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQK7	Gene names	Icmt
Domain Architecture
Description	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT).

ERG24_HUMAN
NC score	0.030019 (rank : 3)	θ value	4.03905 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O76062, O95982, Q8IY06, Q96E64, Q96GZ1	Gene names	TM7SF2, ANG1
Domain Architecture
Description	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Delta14-SR) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR- 1).

GPR45_HUMAN
NC score	0.006016 (rank : 4)	θ value	6.88961 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Y3, Q6NWS4	Gene names	GPR45
Domain Architecture
Description	Probable G-protein coupled receptor 45 (PSP24-alpha) (PSP24-1).

GPR45_MOUSE
NC score	0.005552 (rank : 5)	θ value	8.99809 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	742	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ4	Gene names	Gpr45
Domain Architecture
Description	Probable G-protein coupled receptor 45 (PSP24-alpha) (PSP24-1).