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Network neighborhood for query Sequence : HEXA_HUMAN

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HEXA_HUMAN
SwissProt Accessions	P06865	Gene names	HEXA
Domain Architecture
Description	Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) (N-acetyl- beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HEXA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P06865	Gene names	HEXA
Domain Architecture
Description	Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) (N-acetyl- beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase A).

HEXA_MOUSE
θ value	0 (rank : 2)	NC score	0.998755 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P29416, Q64246	Gene names	Hexa
Domain Architecture
Description	Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) (N-acetyl- beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase A).

HEXB_HUMAN
θ value	1.23469e-174 (rank : 3)	NC score	0.987625 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P07686	Gene names	HEXB
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B) (Cervical cancer proto-oncogene 7) (HCC-7) [Contains: Beta- hexosaminidase beta-B chain; Beta-hexosaminidase beta-A chain].

HEXB_MOUSE
θ value	1.46188e-167 (rank : 4)	NC score	0.988347 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P20060	Gene names	Hexb
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B).

DUX4_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.012800 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

GP1BA_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.010289 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

FA53B_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.017327 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

LX12E_MOUSE
θ value	5.27518 (rank : 8)	NC score	0.008199 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

IRX2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.007304 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	358	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

VAX1_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.006649 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

VAX1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.006611 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

Hits sorted by NC score

HEXA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P06865	Gene names	HEXA
Domain Architecture
Description	Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) (N-acetyl- beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase A).

HEXA_MOUSE
NC score	0.998755 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P29416, Q64246	Gene names	Hexa
Domain Architecture
Description	Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) (N-acetyl- beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase A).

HEXB_MOUSE
NC score	0.988347 (rank : 3)	θ value	1.46188e-167 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P20060	Gene names	Hexb
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B).

HEXB_HUMAN
NC score	0.987625 (rank : 4)	θ value	1.23469e-174 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P07686	Gene names	HEXB
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B) (Cervical cancer proto-oncogene 7) (HCC-7) [Contains: Beta- hexosaminidase beta-B chain; Beta-hexosaminidase beta-A chain].

FA53B_MOUSE
NC score	0.017327 (rank : 5)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

DUX4_HUMAN
NC score	0.012800 (rank : 6)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

GP1BA_HUMAN
NC score	0.010289 (rank : 7)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LX12E_MOUSE
NC score	0.008199 (rank : 8)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

IRX2_HUMAN
NC score	0.007304 (rank : 9)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	358	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

VAX1_HUMAN
NC score	0.006649 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

VAX1_MOUSE
NC score	0.006611 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.