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Network neighborhood for query Sequence : HEM4_HUMAN

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HEM4_HUMAN
SwissProt Accessions	P10746, Q9H2T1	Gene names	UROS
Domain Architecture
Description	Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) (UROIIIS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HEM4_HUMAN
θ value	1.98959e-140 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P10746, Q9H2T1	Gene names	UROS
Domain Architecture
Description	Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) (UROIIIS).

HEM4_MOUSE
θ value	6.88586e-117 (rank : 2)	NC score	0.997090 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P51163	Gene names	Uros, Uros3
Domain Architecture
Description	Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) (UROIIIS).

SIX3_HUMAN
θ value	4.03905 (rank : 3)	NC score	0.026309 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	O95343	Gene names	SIX3
Domain Architecture
Description	Homeobox protein SIX3 (Sine oculis homeobox homolog 3).

SIX3_MOUSE
θ value	4.03905 (rank : 4)	NC score	0.026309 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	Q62233, P70176, P70177	Gene names	Six3
Domain Architecture
Description	Homeobox protein SIX3 (Sine oculis homeobox homolog 3).

P85B_MOUSE
θ value	8.99809 (rank : 5)	NC score	0.008095 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	519	Shared Neighborhood Hits	2
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

Hits sorted by NC score

HEM4_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.98959e-140 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	P10746, Q9H2T1	Gene names	UROS
Domain Architecture
Description	Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) (UROIIIS).

HEM4_MOUSE
NC score	0.997090 (rank : 2)	θ value	6.88586e-117 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P51163	Gene names	Uros, Uros3
Domain Architecture
Description	Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) (UROIIIS).

SIX3_MOUSE
NC score	0.026309 (rank : 3)	θ value	4.03905 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	Q62233, P70176, P70177	Gene names	Six3
Domain Architecture
Description	Homeobox protein SIX3 (Sine oculis homeobox homolog 3).

SIX3_HUMAN
NC score	0.026309 (rank : 4)	θ value	4.03905 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	O95343	Gene names	SIX3
Domain Architecture
Description	Homeobox protein SIX3 (Sine oculis homeobox homolog 3).

P85B_MOUSE
NC score	0.008095 (rank : 5)	θ value	8.99809 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	519	Shared Neighborhood Hits	2
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).