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Network neighborhood for query Sequence : HDA10_HUMAN

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HDA10_HUMAN
SwissProt Accessions	Q969S8, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2	Gene names	HDAC10
Domain Architecture
Description	Histone deacetylase 10 (HD10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HDA10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q969S8, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2	Gene names	HDAC10
Domain Architecture
Description	Histone deacetylase 10 (HD10).

HDA10_MOUSE
θ value	0 (rank : 2)	NC score	0.995709 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P3E7	Gene names	Hdac10
Domain Architecture	No domain graphic available
Description	Histone deacetylase 10 (HD10).

HDAC6_HUMAN
θ value	3.53647e-113 (rank : 3)	NC score	0.921519 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	6.90186e-109 (rank : 4)	NC score	0.931897 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HDAC4_HUMAN
θ value	1.66577e-62 (rank : 5)	NC score	0.848642 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

HDAC9_HUMAN
θ value	5.0155e-59 (rank : 6)	NC score	0.852297 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

HDAC5_HUMAN
θ value	2.32979e-56 (rank : 7)	NC score	0.841093 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HDAC5_MOUSE
θ value	3.974e-56 (rank : 8)	NC score	0.853606 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

HDAC7_HUMAN
θ value	2.57589e-55 (rank : 9)	NC score	0.904786 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HDAC7_MOUSE
θ value	4.39379e-55 (rank : 10)	NC score	0.905276 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HDAC1_HUMAN
θ value	1.33526e-19 (rank : 11)	NC score	0.719344 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
θ value	1.33526e-19 (rank : 12)	NC score	0.719155 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC2_HUMAN
θ value	2.27762e-19 (rank : 13)	NC score	0.717579 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	Q92769, Q5SRI8, Q5SZ86, Q8NEH4	Gene names	HDAC2
Domain Architecture
Description	Histone deacetylase 2 (HD2).

HDAC2_MOUSE
θ value	3.88503e-19 (rank : 14)	NC score	0.716601 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P70288	Gene names	Hdac2, Yy1bp
Domain Architecture
Description	Histone deacetylase 2 (HD2) (YY1 transcription factor-binding protein).

HDAC8_HUMAN
θ value	2.13179e-17 (rank : 15)	NC score	0.745846 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY41, Q9NP76, Q9NYH4	Gene names	HDAC8, HDACL1
Domain Architecture
Description	Histone deacetylase 8 (HD8).

HDAC8_MOUSE
θ value	4.74913e-17 (rank : 16)	NC score	0.743367 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VH37, Q3V270, Q9D0K6	Gene names	Hdac8
Domain Architecture
Description	Histone deacetylase 8 (HD8).

HDAC3_MOUSE
θ value	4.91457e-14 (rank : 17)	NC score	0.683972 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	O88895, O88896	Gene names	Hdac3
Domain Architecture
Description	Histone deacetylase 3 (HD3).

HDAC3_HUMAN
θ value	6.41864e-14 (rank : 18)	NC score	0.682901 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O15379, O43268, Q9UEI5, Q9UEV0	Gene names	HDAC3
Domain Architecture
Description	Histone deacetylase 3 (HD3) (RPD3-2) (SMAP45).

HDA11_HUMAN
θ value	2.28291e-11 (rank : 19)	NC score	0.682798 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q96DB2, Q9H6I7, Q9H6X3, Q9NTC9	Gene names	HDAC11
Domain Architecture
Description	Histone deacetylase 11 (HD11).

HDA11_MOUSE
θ value	4.76016e-09 (rank : 20)	NC score	0.663460 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WA3	Gene names	Hdac11
Domain Architecture
Description	Histone deacetylase 11 (HD11).

MUC7_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.053001 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	538	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.022649 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

XKR6_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.021973 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

PTPRN_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.009521 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

TULP4_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.023934 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

PCLO_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.011471 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	2046	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HRBL_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.016953 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	269	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

NMNA3_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.017506 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T66, Q8N4G1	Gene names	NMNAT3
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 3 (EC 2.7.7.1) (NMN adenylyltransferase 3).

BRD8_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.013018 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

RIMB1_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.010098 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	1376	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

AATK_HUMAN
θ value	5.27518 (rank : 31)	NC score	-0.000316 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	1243	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

MDC1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.024845 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINK1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.000022 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	5.27518 (rank : 34)	NC score	-0.000034 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	1451	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

WBP2_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.015153 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P97765	Gene names	Wbp2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

PSA2_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.009410 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P25787, Q9BU45	Gene names	PSMA2, PSC3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.009418 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P49722	Gene names	Psma2, Lmpc3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

RIMS2_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.008345 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

TR19L_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.009162 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

ZN232_HUMAN
θ value	6.88961 (rank : 40)	NC score	-0.002397 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	754	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

ZN435_HUMAN
θ value	6.88961 (rank : 41)	NC score	-0.002287 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	774	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4T2, Q9H6K2	Gene names	ZNF435, ZSCAN16
Domain Architecture
Description	Zinc finger protein 435 (Zinc finger and SCAN domain-containing protein 16).

I20L2_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.010118 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

RIMS2_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.007534 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

TULP4_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.017941 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

HDAC9_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.418385 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

SYCP3_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.053897 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

Hits sorted by NC score

HDA10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q969S8, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2	Gene names	HDAC10
Domain Architecture
Description	Histone deacetylase 10 (HD10).

HDA10_MOUSE
NC score	0.995709 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P3E7	Gene names	Hdac10
Domain Architecture	No domain graphic available
Description	Histone deacetylase 10 (HD10).

HDAC6_MOUSE
NC score	0.931897 (rank : 3)	θ value	6.90186e-109 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HDAC6_HUMAN
NC score	0.921519 (rank : 4)	θ value	3.53647e-113 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC7_MOUSE
NC score	0.905276 (rank : 5)	θ value	4.39379e-55 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HDAC7_HUMAN
NC score	0.904786 (rank : 6)	θ value	2.57589e-55 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HDAC5_MOUSE
NC score	0.853606 (rank : 7)	θ value	3.974e-56 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

HDAC9_HUMAN
NC score	0.852297 (rank : 8)	θ value	5.0155e-59 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

HDAC4_HUMAN
NC score	0.848642 (rank : 9)	θ value	1.66577e-62 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

HDAC5_HUMAN
NC score	0.841093 (rank : 10)	θ value	2.32979e-56 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HDAC8_HUMAN
NC score	0.745846 (rank : 11)	θ value	2.13179e-17 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY41, Q9NP76, Q9NYH4	Gene names	HDAC8, HDACL1
Domain Architecture
Description	Histone deacetylase 8 (HD8).

HDAC8_MOUSE
NC score	0.743367 (rank : 12)	θ value	4.74913e-17 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VH37, Q3V270, Q9D0K6	Gene names	Hdac8
Domain Architecture
Description	Histone deacetylase 8 (HD8).

HDAC1_HUMAN
NC score	0.719344 (rank : 13)	θ value	1.33526e-19 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
NC score	0.719155 (rank : 14)	θ value	1.33526e-19 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC2_HUMAN
NC score	0.717579 (rank : 15)	θ value	2.27762e-19 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	Q92769, Q5SRI8, Q5SZ86, Q8NEH4	Gene names	HDAC2
Domain Architecture
Description	Histone deacetylase 2 (HD2).

HDAC2_MOUSE
NC score	0.716601 (rank : 16)	θ value	3.88503e-19 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P70288	Gene names	Hdac2, Yy1bp
Domain Architecture
Description	Histone deacetylase 2 (HD2) (YY1 transcription factor-binding protein).

HDAC3_MOUSE
NC score	0.683972 (rank : 17)	θ value	4.91457e-14 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	O88895, O88896	Gene names	Hdac3
Domain Architecture
Description	Histone deacetylase 3 (HD3).

HDAC3_HUMAN
NC score	0.682901 (rank : 18)	θ value	6.41864e-14 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O15379, O43268, Q9UEI5, Q9UEV0	Gene names	HDAC3
Domain Architecture
Description	Histone deacetylase 3 (HD3) (RPD3-2) (SMAP45).

HDA11_HUMAN
NC score	0.682798 (rank : 19)	θ value	2.28291e-11 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q96DB2, Q9H6I7, Q9H6X3, Q9NTC9	Gene names	HDAC11
Domain Architecture
Description	Histone deacetylase 11 (HD11).

HDA11_MOUSE
NC score	0.663460 (rank : 20)	θ value	4.76016e-09 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WA3	Gene names	Hdac11
Domain Architecture
Description	Histone deacetylase 11 (HD11).

HDAC9_MOUSE
NC score	0.418385 (rank : 21)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

SYCP3_HUMAN
NC score	0.053897 (rank : 22)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

MUC7_HUMAN
NC score	0.053001 (rank : 23)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	538	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MDC1_HUMAN
NC score	0.024845 (rank : 24)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TULP4_HUMAN
NC score	0.023934 (rank : 25)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NACAM_MOUSE
NC score	0.022649 (rank : 26)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

XKR6_HUMAN
NC score	0.021973 (rank : 27)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

TULP4_MOUSE
NC score	0.017941 (rank : 28)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NMNA3_HUMAN
NC score	0.017506 (rank : 29)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T66, Q8N4G1	Gene names	NMNAT3
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 3 (EC 2.7.7.1) (NMN adenylyltransferase 3).

HRBL_MOUSE
NC score	0.016953 (rank : 30)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	269	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

WBP2_MOUSE
NC score	0.015153 (rank : 31)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P97765	Gene names	Wbp2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

BRD8_HUMAN
NC score	0.013018 (rank : 32)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

PCLO_HUMAN
NC score	0.011471 (rank : 33)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	2046	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

I20L2_HUMAN
NC score	0.010118 (rank : 34)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

RIMB1_MOUSE
NC score	0.010098 (rank : 35)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	1376	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PTPRN_MOUSE
NC score	0.009521 (rank : 36)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PSA2_MOUSE
NC score	0.009418 (rank : 37)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P49722	Gene names	Psma2, Lmpc3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA2_HUMAN
NC score	0.009410 (rank : 38)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P25787, Q9BU45	Gene names	PSMA2, PSC3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

TR19L_HUMAN
NC score	0.009162 (rank : 39)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

RIMS2_HUMAN
NC score	0.008345 (rank : 40)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.007534 (rank : 41)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

MINK1_HUMAN
NC score	0.000022 (rank : 42)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
NC score	-0.000034 (rank : 43)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	1451	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

AATK_HUMAN
NC score	-0.000316 (rank : 44)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	1243	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ZN435_HUMAN
NC score	-0.002287 (rank : 45)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	774	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4T2, Q9H6K2	Gene names	ZNF435, ZSCAN16
Domain Architecture
Description	Zinc finger protein 435 (Zinc finger and SCAN domain-containing protein 16).

ZN232_HUMAN
NC score	-0.002397 (rank : 46)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	754	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).