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Network neighborhood for query Sequence : GDE_HUMAN

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GDE_HUMAN
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GDE_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

DPOLZ_HUMAN
θ value	1.81305 (rank : 2)	NC score	0.031972 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

SETX_HUMAN
θ value	3.0926 (rank : 3)	NC score	0.028391 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	368	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

KS6A4_MOUSE
θ value	5.27518 (rank : 4)	NC score	0.003630 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	866	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

TITIN_HUMAN
θ value	5.27518 (rank : 5)	NC score	0.005473 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CAPON_MOUSE
θ value	6.88961 (rank : 6)	NC score	0.023027 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NOG1_MOUSE
θ value	6.88961 (rank : 7)	NC score	0.022112 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

ZFY2_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.002249 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

MYOM1_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.011818 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	415	Shared Neighborhood Hits	3
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

Hits sorted by NC score

GDE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P35573, P78354, P78544, Q9UF08	Gene names	AGL, GDE
Domain Architecture
Description	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha- glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (EC 3.2.1.33) (Amylo-1,6-glucosidase) (Dextrin 6-alpha-D-glucosidase)].

DPOLZ_HUMAN
NC score	0.031972 (rank : 2)	θ value	1.81305 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

SETX_HUMAN
NC score	0.028391 (rank : 3)	θ value	3.0926 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	368	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

CAPON_MOUSE
NC score	0.023027 (rank : 4)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NOG1_MOUSE
NC score	0.022112 (rank : 5)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

MYOM1_MOUSE
NC score	0.011818 (rank : 6)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	415	Shared Neighborhood Hits	3
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

TITIN_HUMAN
NC score	0.005473 (rank : 7)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

KS6A4_MOUSE
NC score	0.003630 (rank : 8)	θ value	5.27518 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	866	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

ZFY2_MOUSE
NC score	0.002249 (rank : 9)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.