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Network neighborhood for query Sequence : FANCB_HUMAN

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FANCB_HUMAN
SwissProt Accessions	Q8NB91, Q7Z2U2, Q86XG1	Gene names	FANCB
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein (Protein FACB) (Fanconi anemia- associated polypeptide of 95 kDa) (FAAP95).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FANCB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB91, Q7Z2U2, Q86XG1	Gene names	FANCB
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein (Protein FACB) (Fanconi anemia- associated polypeptide of 95 kDa) (FAAP95).

FANCB_MOUSE
θ value	8.0776e-142 (rank : 2)	NC score	0.940425 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5XJY6	Gene names	Fancb
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein homolog (Protein FACB).

ROCK2_MOUSE
θ value	0.125558 (rank : 3)	NC score	0.018016 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	2072	Shared Neighborhood Hits	12
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

DYH9_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.035901 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

ROCK2_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.017293 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	2073	Shared Neighborhood Hits	12
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

RUFY2_MOUSE
θ value	0.47712 (rank : 6)	NC score	0.027425 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ADA32_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.016912 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

NUP88_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.046573 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

HIP1_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.017487 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	1016	Shared Neighborhood Hits	12
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

BBS2_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.023334 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWF6	Gene names	Bbs2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein homolog.

GOGA4_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.013848 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	2034	Shared Neighborhood Hits	12
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

OPTN_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.019687 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	827	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CT172_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.023028 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

DNL3_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.016359 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

MYH10_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.010006 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1620	Shared Neighborhood Hits	13
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ROCK1_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.013385 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	2000	Shared Neighborhood Hits	12
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CJ118_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.014068 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	937	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

KIF3C_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.008957 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

Hits sorted by NC score

FANCB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB91, Q7Z2U2, Q86XG1	Gene names	FANCB
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein (Protein FACB) (Fanconi anemia- associated polypeptide of 95 kDa) (FAAP95).

FANCB_MOUSE
NC score	0.940425 (rank : 2)	θ value	8.0776e-142 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5XJY6	Gene names	Fancb
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein homolog (Protein FACB).

NUP88_HUMAN
NC score	0.046573 (rank : 3)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

DYH9_HUMAN
NC score	0.035901 (rank : 4)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

RUFY2_MOUSE
NC score	0.027425 (rank : 5)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

BBS2_MOUSE
NC score	0.023334 (rank : 6)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWF6	Gene names	Bbs2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein homolog.

CT172_HUMAN
NC score	0.023028 (rank : 7)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

OPTN_HUMAN
NC score	0.019687 (rank : 8)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	827	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

ROCK2_MOUSE
NC score	0.018016 (rank : 9)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	2072	Shared Neighborhood Hits	12
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

HIP1_HUMAN
NC score	0.017487 (rank : 10)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	1016	Shared Neighborhood Hits	12
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

ROCK2_HUMAN
NC score	0.017293 (rank : 11)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	2073	Shared Neighborhood Hits	12
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ADA32_HUMAN
NC score	0.016912 (rank : 12)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

DNL3_HUMAN
NC score	0.016359 (rank : 13)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

CJ118_HUMAN
NC score	0.014068 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	937	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

GOGA4_HUMAN
NC score	0.013848 (rank : 15)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	2034	Shared Neighborhood Hits	12
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

ROCK1_HUMAN
NC score	0.013385 (rank : 16)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	2000	Shared Neighborhood Hits	12
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MYH10_HUMAN
NC score	0.010006 (rank : 17)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	1620	Shared Neighborhood Hits	13
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

KIF3C_HUMAN
NC score	0.008957 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.