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Network neighborhood for query Sequence : ERG25_HUMAN

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ERG25_HUMAN
SwissProt Accessions	Q15800, Q32Q24	Gene names	SC4MOL, DESP4, ERG25
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERG25_HUMAN
θ value	1.90044e-183 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q15800, Q32Q24	Gene names	SC4MOL, DESP4, ERG25
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

ERG25_MOUSE
θ value	6.7907e-165 (rank : 2)	NC score	0.999315 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CRA4, Q543V8	Gene names	Sc4mol
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

CH25H_MOUSE
θ value	6.84181e-24 (rank : 3)	NC score	0.750091 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0F5, Q3TUM6, Q8CHQ2	Gene names	Ch25h
Domain Architecture	No domain graphic available
Description	Cholesterol 25-hydroxylase (EC 1.14.99.38) (Cholesterol 25- monooxygenase) (m25OH).

CH25H_HUMAN
θ value	3.39556e-23 (rank : 4)	NC score	0.755445 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O95992	Gene names	CH25H
Domain Architecture	No domain graphic available
Description	Cholesterol 25-hydroxylase (EC 1.14.99.38) (Cholesterol 25- monooxygenase) (h25OH).

CE004_HUMAN
θ value	3.75424e-22 (rank : 5)	NC score	0.746075 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IV6, Q9BSX6, Q9H8C7	Gene names	C5orf4
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf4.

SC5D_HUMAN
θ value	2.60593e-15 (rank : 6)	NC score	0.644700 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O75845, O00119, Q9UK15	Gene names	SC5DL
Domain Architecture
Description	Lathosterol oxidase (EC 1.14.21.6) (Lathosterol 5-desaturase) (Delta- 7-sterol 5-desaturase) (C-5 sterol desaturase) (Sterol-C5-desaturase).

SC5D_MOUSE
θ value	2.60593e-15 (rank : 7)	NC score	0.637009 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O88822	Gene names	Sc5dl, Sc5d
Domain Architecture
Description	Lathosterol oxidase (EC 1.14.21.6) (Lathosterol 5-desaturase) (Delta- 7-sterol 5-desaturase) (C-5 sterol desaturase) (Sterol-C5-desaturase).

CCR3_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.001224 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	781	Shared Neighborhood Hits	2
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

CAC1B_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.004621 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CD1D2_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.005553 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	P11610	Gene names	Cd1d2, Cd1.2
Domain Architecture
Description	T-cell surface glycoprotein CD1d2 precursor (CD1.2 antigen).

Hits sorted by NC score

ERG25_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.90044e-183 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q15800, Q32Q24	Gene names	SC4MOL, DESP4, ERG25
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

ERG25_MOUSE
NC score	0.999315 (rank : 2)	θ value	6.7907e-165 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CRA4, Q543V8	Gene names	Sc4mol
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

CH25H_HUMAN
NC score	0.755445 (rank : 3)	θ value	3.39556e-23 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O95992	Gene names	CH25H
Domain Architecture	No domain graphic available
Description	Cholesterol 25-hydroxylase (EC 1.14.99.38) (Cholesterol 25- monooxygenase) (h25OH).

CH25H_MOUSE
NC score	0.750091 (rank : 4)	θ value	6.84181e-24 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0F5, Q3TUM6, Q8CHQ2	Gene names	Ch25h
Domain Architecture	No domain graphic available
Description	Cholesterol 25-hydroxylase (EC 1.14.99.38) (Cholesterol 25- monooxygenase) (m25OH).

CE004_HUMAN
NC score	0.746075 (rank : 5)	θ value	3.75424e-22 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IV6, Q9BSX6, Q9H8C7	Gene names	C5orf4
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf4.

SC5D_HUMAN
NC score	0.644700 (rank : 6)	θ value	2.60593e-15 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O75845, O00119, Q9UK15	Gene names	SC5DL
Domain Architecture
Description	Lathosterol oxidase (EC 1.14.21.6) (Lathosterol 5-desaturase) (Delta- 7-sterol 5-desaturase) (C-5 sterol desaturase) (Sterol-C5-desaturase).

SC5D_MOUSE
NC score	0.637009 (rank : 7)	θ value	2.60593e-15 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O88822	Gene names	Sc5dl, Sc5d
Domain Architecture
Description	Lathosterol oxidase (EC 1.14.21.6) (Lathosterol 5-desaturase) (Delta- 7-sterol 5-desaturase) (C-5 sterol desaturase) (Sterol-C5-desaturase).

CD1D2_MOUSE
NC score	0.005553 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	P11610	Gene names	Cd1d2, Cd1.2
Domain Architecture
Description	T-cell surface glycoprotein CD1d2 precursor (CD1.2 antigen).

CAC1B_MOUSE
NC score	0.004621 (rank : 9)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CCR3_MOUSE
NC score	0.001224 (rank : 10)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	781	Shared Neighborhood Hits	2
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).