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Network neighborhood for query Sequence : DHDDS_HUMAN

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DHDDS_HUMAN
SwissProt Accessions	Q86SQ9, Q8NE90, Q9BTG5, Q9BTK3, Q9H905	Gene names	DHDDS, HDS
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DHDDS_HUMAN
θ value	8.53067e-184 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q86SQ9, Q8NE90, Q9BTG5, Q9BTK3, Q9H905	Gene names	DHDDS, HDS
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

DHDDS_MOUSE
θ value	6.77497e-173 (rank : 2)	NC score	0.996339 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

ENAH_MOUSE
θ value	0.00869519 (rank : 3)	NC score	0.075914 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	919	Shared Neighborhood Hits	8
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TRHY_HUMAN
θ value	0.0961366 (rank : 4)	NC score	0.026568 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	1385	Shared Neighborhood Hits	8
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

XE7_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.046978 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	738	Shared Neighborhood Hits	9
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BST1_MOUSE
θ value	4.03905 (rank : 6)	NC score	0.027076 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q64277, Q8BRY3	Gene names	Bst1, Bp-3, Bp3, Ly65
Domain Architecture
Description	ADP-ribosyl cyclase 2 precursor (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Bone marrow stromal antigen 1) (BST- 1) (BP-3 alloantigen) (Antigen BP3) (CD157 antigen).

ROCK1_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.006264 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	2126	Shared Neighborhood Hits	10
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

INCE_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.012849 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	978	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SM1L2_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.014660 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	918	Shared Neighborhood Hits	9
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

AZI1_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.018873 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	1000	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

INVS_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.012244 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	609	Shared Neighborhood Hits	5
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MYH11_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.008602 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1806	Shared Neighborhood Hits	10
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

DESP_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.015453 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	1470	Shared Neighborhood Hits	11
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

Hits sorted by NC score

DHDDS_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.53067e-184 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q86SQ9, Q8NE90, Q9BTG5, Q9BTK3, Q9H905	Gene names	DHDDS, HDS
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

DHDDS_MOUSE
NC score	0.996339 (rank : 2)	θ value	6.77497e-173 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

ENAH_MOUSE
NC score	0.075914 (rank : 3)	θ value	0.00869519 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	919	Shared Neighborhood Hits	8
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

XE7_HUMAN
NC score	0.046978 (rank : 4)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	738	Shared Neighborhood Hits	9
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BST1_MOUSE
NC score	0.027076 (rank : 5)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q64277, Q8BRY3	Gene names	Bst1, Bp-3, Bp3, Ly65
Domain Architecture
Description	ADP-ribosyl cyclase 2 precursor (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Bone marrow stromal antigen 1) (BST- 1) (BP-3 alloantigen) (Antigen BP3) (CD157 antigen).

TRHY_HUMAN
NC score	0.026568 (rank : 6)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	1385	Shared Neighborhood Hits	8
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AZI1_HUMAN
NC score	0.018873 (rank : 7)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	1000	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

DESP_HUMAN
NC score	0.015453 (rank : 8)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1470	Shared Neighborhood Hits	11
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

SM1L2_MOUSE
NC score	0.014660 (rank : 9)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	918	Shared Neighborhood Hits	9
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

INCE_HUMAN
NC score	0.012849 (rank : 10)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	978	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INVS_MOUSE
NC score	0.012244 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	609	Shared Neighborhood Hits	5
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MYH11_HUMAN
NC score	0.008602 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1806	Shared Neighborhood Hits	10
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ROCK1_MOUSE
NC score	0.006264 (rank : 13)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	2126	Shared Neighborhood Hits	10
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).