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Network neighborhood for query Sequence : COX10_HUMAN

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COX10_HUMAN
SwissProt Accessions	Q12887, O15334, Q969F7	Gene names	COX10
Domain Architecture
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COX10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q12887, O15334, Q969F7	Gene names	COX10
Domain Architecture
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

COX10_MOUSE
θ value	0 (rank : 2)	NC score	0.985818 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

COQ2_HUMAN
θ value	7.59969e-07 (rank : 3)	NC score	0.386215 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q96H96, O95331, Q684R2	Gene names	COQ2, CL640
Domain Architecture	No domain graphic available
Description	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial precursor (EC 2.5.1.-) (PHB:polyprenyltransferase) (hCOQ2).

COQ2_MOUSE
θ value	9.92553e-07 (rank : 4)	NC score	0.383395 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q66JT7, Q9D7M9	Gene names	Coq2
Domain Architecture	No domain graphic available
Description	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial precursor (EC 2.5.1.-) (PHB:polyprenyltransferase).

MACF1_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.027568 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.030926 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1321	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

ETBR2_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.029750 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

MACF1_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.026618 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1313	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TSSK2_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.003687 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	819	Shared Neighborhood Hits	2
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).

ETBR2_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.024244 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	487	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JG2, O88313, Q80UB9, Q99JG1	Gene names	Gpr37l1, Etbrlp2
Domain Architecture	No domain graphic available
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

EMBP_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.024256 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	P13727, Q14227	Gene names	PRG2, MBP
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (EMBP) (Pregnancy-associated major basic protein) (Proteoglycan 2, bone marrow) (BMPG).

SEM4G_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.007834 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

GP161_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.006386 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	690	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

DBF4_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.016407 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

Hits sorted by NC score

COX10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q12887, O15334, Q969F7	Gene names	COX10
Domain Architecture
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

COX10_MOUSE
NC score	0.985818 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

COQ2_HUMAN
NC score	0.386215 (rank : 3)	θ value	7.59969e-07 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q96H96, O95331, Q684R2	Gene names	COQ2, CL640
Domain Architecture	No domain graphic available
Description	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial precursor (EC 2.5.1.-) (PHB:polyprenyltransferase) (hCOQ2).

COQ2_MOUSE
NC score	0.383395 (rank : 4)	θ value	9.92553e-07 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q66JT7, Q9D7M9	Gene names	Coq2
Domain Architecture	No domain graphic available
Description	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial precursor (EC 2.5.1.-) (PHB:polyprenyltransferase).

MACF4_HUMAN
NC score	0.030926 (rank : 5)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	1321	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

ETBR2_HUMAN
NC score	0.029750 (rank : 6)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

MACF1_HUMAN
NC score	0.027568 (rank : 7)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
NC score	0.026618 (rank : 8)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1313	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

EMBP_HUMAN
NC score	0.024256 (rank : 9)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	P13727, Q14227	Gene names	PRG2, MBP
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (EMBP) (Pregnancy-associated major basic protein) (Proteoglycan 2, bone marrow) (BMPG).

ETBR2_MOUSE
NC score	0.024244 (rank : 10)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	487	Shared Neighborhood Hits	5
SwissProt Accessions	Q99JG2, O88313, Q80UB9, Q99JG1	Gene names	Gpr37l1, Etbrlp2
Domain Architecture	No domain graphic available
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

DBF4_HUMAN
NC score	0.016407 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

SEM4G_MOUSE
NC score	0.007834 (rank : 12)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

GP161_HUMAN
NC score	0.006386 (rank : 13)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	690	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

TSSK2_MOUSE
NC score	0.003687 (rank : 14)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	819	Shared Neighborhood Hits	2
SwissProt Accessions	O54863	Gene names	Tssk2, Stk22b
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B).