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Network neighborhood for query Sequence : COTE1_HUMAN

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COTE1_HUMAN
SwissProt Accessions	P81408	Gene names	C1orf2, COTE1
Domain Architecture	No domain graphic available
Description	Protein COTE1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COTE1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P81408	Gene names	C1orf2, COTE1
Domain Architecture	No domain graphic available
Description	Protein COTE1.

SPEG_MOUSE
θ value	0.00390308 (rank : 2)	NC score	0.028963 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DOK3_HUMAN
θ value	0.813845 (rank : 3)	NC score	0.050499 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

CACB1_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.033229 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

RTN2_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.062885 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

FCERB_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.059413 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q01362	Gene names	MS4A2, FCER1B, IGER
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor subunit beta (FcERI) (IgE Fc receptor, subunit beta) (Fc epsilon receptor I beta-chain).

GLI2_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.010399 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	971	Shared Neighborhood Hits	8
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ZNT2_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.048957 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRI3	Gene names	SLC30A2
Domain Architecture	No domain graphic available
Description	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2).

ADA19_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.025302 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

BPA1_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.017017 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1477	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ADA19_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.023216 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	381	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MDC1_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.023026 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1446	Shared Neighborhood Hits	8
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RP3A_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.019105 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	305	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RTN2_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.049216 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

ABI1_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.019597 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ADA15_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.021885 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

CI061_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.042507 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q15884, Q5T6C8, Q5T6C9, Q96N10	Gene names	C9orf61, X123
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf61 (Protein X123).

CN065_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.062827 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

LAX1_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.043004 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

UB7I1_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.029054 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

ARI1A_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.025382 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	787	Shared Neighborhood Hits	7
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BPAEA_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.015994 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	1369	Shared Neighborhood Hits	4
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD21_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.011685 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

FRAS1_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.013361 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	759	Shared Neighborhood Hits	7
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

M4A8B_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.039191 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY19, Q8TCA5	Gene names	MS4A8B, 4SPAN4
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 8B (Four-span transmembrane protein 4).

MYPC3_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.020864 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

RTKN_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.030534 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

BST2_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.040689 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q8, Q8CEY7	Gene names	Bst2
Domain Architecture	No domain graphic available
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

CLDND_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.042636 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY35, Q502Y8, Q6UVX2, Q9BUZ9, Q9NZZ5, Q9Y4S9	Gene names	CLDND1, C3orf4
Domain Architecture
Description	Claudin domain-containing protein 1 (Membrane protein GENX-3745).

CLDND_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.042691 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQX5, Q3U7C4	Gene names	Cldnd1, D11Moh34
Domain Architecture
Description	Claudin domain-containing protein 1.

ELOA3_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.032275 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

K1849_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.016477 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

S23IP_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.022121 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	363	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

KR102_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.013606 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

MISS_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.023282 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PDE3A_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.010238 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDZD3_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.012359 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

RASL2_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.011561 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

TAL1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.013609 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

ZN689_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.001284 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS4, Q658J5	Gene names	ZNF689
Domain Architecture	No domain graphic available
Description	Zinc finger protein 689.

Hits sorted by NC score

COTE1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P81408	Gene names	C1orf2, COTE1
Domain Architecture	No domain graphic available
Description	Protein COTE1.

RTN2_HUMAN
NC score	0.062885 (rank : 2)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

CN065_HUMAN
NC score	0.062827 (rank : 3)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

FCERB_HUMAN
NC score	0.059413 (rank : 4)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q01362	Gene names	MS4A2, FCER1B, IGER
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor subunit beta (FcERI) (IgE Fc receptor, subunit beta) (Fc epsilon receptor I beta-chain).

DOK3_HUMAN
NC score	0.050499 (rank : 5)	θ value	0.813845 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

RTN2_MOUSE
NC score	0.049216 (rank : 6)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

ZNT2_HUMAN
NC score	0.048957 (rank : 7)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRI3	Gene names	SLC30A2
Domain Architecture	No domain graphic available
Description	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2).

LAX1_MOUSE
NC score	0.043004 (rank : 8)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

CLDND_MOUSE
NC score	0.042691 (rank : 9)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQX5, Q3U7C4	Gene names	Cldnd1, D11Moh34
Domain Architecture
Description	Claudin domain-containing protein 1.

CLDND_HUMAN
NC score	0.042636 (rank : 10)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY35, Q502Y8, Q6UVX2, Q9BUZ9, Q9NZZ5, Q9Y4S9	Gene names	CLDND1, C3orf4
Domain Architecture
Description	Claudin domain-containing protein 1 (Membrane protein GENX-3745).

CI061_HUMAN
NC score	0.042507 (rank : 11)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q15884, Q5T6C8, Q5T6C9, Q96N10	Gene names	C9orf61, X123
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf61 (Protein X123).

BST2_MOUSE
NC score	0.040689 (rank : 12)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q8, Q8CEY7	Gene names	Bst2
Domain Architecture	No domain graphic available
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

M4A8B_HUMAN
NC score	0.039191 (rank : 13)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY19, Q8TCA5	Gene names	MS4A8B, 4SPAN4
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 8B (Four-span transmembrane protein 4).

CACB1_HUMAN
NC score	0.033229 (rank : 14)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

ELOA3_HUMAN
NC score	0.032275 (rank : 15)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

RTKN_HUMAN
NC score	0.030534 (rank : 16)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

UB7I1_MOUSE
NC score	0.029054 (rank : 17)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

SPEG_MOUSE
NC score	0.028963 (rank : 18)	θ value	0.00390308 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ARI1A_HUMAN
NC score	0.025382 (rank : 19)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	787	Shared Neighborhood Hits	7
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ADA19_MOUSE
NC score	0.025302 (rank : 20)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

MISS_MOUSE
NC score	0.023282 (rank : 21)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ADA19_HUMAN
NC score	0.023216 (rank : 22)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	381	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MDC1_HUMAN
NC score	0.023026 (rank : 23)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	1446	Shared Neighborhood Hits	8
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

S23IP_MOUSE
NC score	0.022121 (rank : 24)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	363	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ADA15_MOUSE
NC score	0.021885 (rank : 25)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

MYPC3_MOUSE
NC score	0.020864 (rank : 26)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ABI1_HUMAN
NC score	0.019597 (rank : 27)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

RP3A_HUMAN
NC score	0.019105 (rank : 28)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	305	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BPA1_MOUSE
NC score	0.017017 (rank : 29)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	1477	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

K1849_MOUSE
NC score	0.016477 (rank : 30)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

BPAEA_HUMAN
NC score	0.015994 (rank : 31)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1369	Shared Neighborhood Hits	4
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TAL1_HUMAN
NC score	0.013609 (rank : 32)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

KR102_HUMAN
NC score	0.013606 (rank : 33)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

FRAS1_HUMAN
NC score	0.013361 (rank : 34)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	759	Shared Neighborhood Hits	7
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PDZD3_HUMAN
NC score	0.012359 (rank : 35)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

CCD21_MOUSE
NC score	0.011685 (rank : 36)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RASL2_HUMAN
NC score	0.011561 (rank : 37)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

GLI2_HUMAN
NC score	0.010399 (rank : 38)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	971	Shared Neighborhood Hits	8
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

PDE3A_MOUSE
NC score	0.010238 (rank : 39)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

ZN689_HUMAN
NC score	0.001284 (rank : 40)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS4, Q658J5	Gene names	ZNF689
Domain Architecture	No domain graphic available
Description	Zinc finger protein 689.