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Network neighborhood for query Sequence : COPZ1_HUMAN

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COPZ1_HUMAN
SwissProt Accessions	P61923, Q9Y3C3	Gene names	COPZ1, COPZ
Domain Architecture
Description	Coatomer subunit zeta-1 (Zeta-1 coat protein) (Zeta-1 COP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COPZ1_HUMAN
θ value	1.65039e-94 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P61923, Q9Y3C3	Gene names	COPZ1, COPZ
Domain Architecture
Description	Coatomer subunit zeta-1 (Zeta-1 coat protein) (Zeta-1 COP).

COPZ1_MOUSE
θ value	1.65039e-94 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P61924, Q9Y3C3	Gene names	Copz1, Copz
Domain Architecture
Description	Coatomer subunit zeta-1 (Zeta-1 coat protein) (Zeta-1 COP).

COPZ2_HUMAN
θ value	2.83479e-70 (rank : 3)	NC score	0.981831 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P299	Gene names	COPZ2
Domain Architecture
Description	Coatomer subunit zeta-2 (Zeta-2 coat protein) (Zeta-2 COP).

COPZ2_MOUSE
θ value	1.40689e-69 (rank : 4)	NC score	0.969679 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHH9	Gene names	Copz2
Domain Architecture
Description	Coatomer subunit zeta-2 (Zeta-2 coat protein) (Zeta-2 COP).

AP3S2_HUMAN
θ value	1.09739e-05 (rank : 6)	NC score	0.409524 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P59780, O09077, O09149, Q99589	Gene names	AP3S2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP3S2_MOUSE
θ value	1.09739e-05 (rank : 7)	NC score	0.409524 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BSZ2, O09077, O09149, Q3UDG7, Q8CAY1, Q99589	Gene names	Ap3s2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP1S3_HUMAN
θ value	3.19293e-05 (rank : 8)	NC score	0.318205 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PC3, Q8WTY1, Q96DD1	Gene names	AP1S3
Domain Architecture
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP3S1_HUMAN
θ value	5.44631e-05 (rank : 9)	NC score	0.404939 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q92572, O00647, O00676, O00721, O00727, Q6ICQ2	Gene names	AP3S1, CLAPS3
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin) (Clathrin-associated/assembly/adapter protein, small 3).

AP3S1_MOUSE
θ value	5.44631e-05 (rank : 10)	NC score	0.404939 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DCR2, O88670	Gene names	Ap3s1
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin).

AP1S2_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.256616 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DB50, Q543R7	Gene names	Ap1s2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP1S1_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.241313 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P61966, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	AP1S1, AP19, CLAPS1
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP1S1_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.241313 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P61967, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	Ap1s1, Ap19
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP1S2_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.254940 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	P56377, O95326, Q9H2N6	Gene names	AP1S2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

OSBL6_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.009079 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

AP2S1_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.198357 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P53680, O75977, Q6PK67	Gene names	AP2S1, AP17, CLAPS2
Domain Architecture
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Clathrin coat assembly protein AP17) (Clathrin coat- associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (HA2 17 kDa subunit) (Clathrin assembly protein 2 small chain).

AP4S1_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.260848 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y587	Gene names	AP4S1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP4S1_MOUSE
θ value	θ > 10 (rank : 19)	NC score	0.254438 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVL1	Gene names	Ap4s1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

Hits sorted by NC score

COPZ1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.65039e-94 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P61923, Q9Y3C3	Gene names	COPZ1, COPZ
Domain Architecture
Description	Coatomer subunit zeta-1 (Zeta-1 coat protein) (Zeta-1 COP).

COPZ1_MOUSE
NC score	0.999962 (rank : 2)	θ value	1.65039e-94 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P61924, Q9Y3C3	Gene names	Copz1, Copz
Domain Architecture
Description	Coatomer subunit zeta-1 (Zeta-1 coat protein) (Zeta-1 COP).

COPZ2_HUMAN
NC score	0.981831 (rank : 3)	θ value	2.83479e-70 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P299	Gene names	COPZ2
Domain Architecture
Description	Coatomer subunit zeta-2 (Zeta-2 coat protein) (Zeta-2 COP).

COPZ2_MOUSE
NC score	0.969679 (rank : 4)	θ value	1.40689e-69 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHH9	Gene names	Copz2
Domain Architecture
Description	Coatomer subunit zeta-2 (Zeta-2 coat protein) (Zeta-2 COP).

AP3S2_HUMAN
NC score	0.409524 (rank : 5)	θ value	1.09739e-05 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P59780, O09077, O09149, Q99589	Gene names	AP3S2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP3S2_MOUSE
NC score	0.409524 (rank : 6)	θ value	1.09739e-05 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BSZ2, O09077, O09149, Q3UDG7, Q8CAY1, Q99589	Gene names	Ap3s2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP3S1_HUMAN
NC score	0.404939 (rank : 7)	θ value	5.44631e-05 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q92572, O00647, O00676, O00721, O00727, Q6ICQ2	Gene names	AP3S1, CLAPS3
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin) (Clathrin-associated/assembly/adapter protein, small 3).

AP3S1_MOUSE
NC score	0.404939 (rank : 8)	θ value	5.44631e-05 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DCR2, O88670	Gene names	Ap3s1
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin).

AP1S3_HUMAN
NC score	0.318205 (rank : 10)	θ value	3.19293e-05 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PC3, Q8WTY1, Q96DD1	Gene names	AP1S3
Domain Architecture
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP4S1_HUMAN
NC score	0.260848 (rank : 11)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y587	Gene names	AP4S1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP1S2_MOUSE
NC score	0.256616 (rank : 12)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DB50, Q543R7	Gene names	Ap1s2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP1S2_HUMAN
NC score	0.254940 (rank : 13)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	P56377, O95326, Q9H2N6	Gene names	AP1S2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP4S1_MOUSE
NC score	0.254438 (rank : 14)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVL1	Gene names	Ap4s1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP1S1_HUMAN
NC score	0.241313 (rank : 15)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P61966, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	AP1S1, AP19, CLAPS1
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP1S1_MOUSE
NC score	0.241313 (rank : 16)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P61967, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	Ap1s1, Ap19
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP2S1_HUMAN
NC score	0.198357 (rank : 17)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P53680, O75977, Q6PK67	Gene names	AP2S1, AP17, CLAPS2
Domain Architecture
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Clathrin coat assembly protein AP17) (Clathrin coat- associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (HA2 17 kDa subunit) (Clathrin assembly protein 2 small chain).

OSBL6_HUMAN
NC score	0.009079 (rank : 19)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).