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Network neighborhood for query Sequence : COMT_HUMAN

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COMT_HUMAN
SwissProt Accessions	P21964	Gene names	COMT
Domain Architecture
Description	Catechol O-methyltransferase (EC 2.1.1.6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COMT_HUMAN
θ value	9.22056e-146 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P21964	Gene names	COMT
Domain Architecture
Description	Catechol O-methyltransferase (EC 2.1.1.6).

COMT_MOUSE
θ value	1.69605e-115 (rank : 2)	NC score	0.996746 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O88587	Gene names	Comt
Domain Architecture
Description	Catechol O-methyltransferase (EC 2.1.1.6).

CMTD1_MOUSE
θ value	0.00035302 (rank : 3)	NC score	0.318059 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIG7	Gene names	Comtd1
Domain Architecture	No domain graphic available
Description	Catechol-O-methyltransferase domain-containing protein 1 (EC 2.1.1.-).

CMTD1_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.282212 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VU5, Q8TE79	Gene names	COMTD1
Domain Architecture	No domain graphic available
Description	Catechol-O-methyltransferase domain-containing protein 1 (EC 2.1.1.-).

HEMK2_HUMAN
θ value	5.27518 (rank : 5)	NC score	0.060476 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5N5	Gene names	HEMK2, C21orf127, N6AMT1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P).

NC6IP_HUMAN
θ value	6.88961 (rank : 6)	NC score	0.030027 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

OSBL7_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.011328 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

NC6IP_MOUSE
θ value	8.99809 (rank : 8)	NC score	0.026902 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

Hits sorted by NC score

COMT_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.22056e-146 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P21964	Gene names	COMT
Domain Architecture
Description	Catechol O-methyltransferase (EC 2.1.1.6).

COMT_MOUSE
NC score	0.996746 (rank : 2)	θ value	1.69605e-115 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O88587	Gene names	Comt
Domain Architecture
Description	Catechol O-methyltransferase (EC 2.1.1.6).

CMTD1_MOUSE
NC score	0.318059 (rank : 3)	θ value	0.00035302 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIG7	Gene names	Comtd1
Domain Architecture	No domain graphic available
Description	Catechol-O-methyltransferase domain-containing protein 1 (EC 2.1.1.-).

CMTD1_HUMAN
NC score	0.282212 (rank : 4)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VU5, Q8TE79	Gene names	COMTD1
Domain Architecture	No domain graphic available
Description	Catechol-O-methyltransferase domain-containing protein 1 (EC 2.1.1.-).

HEMK2_HUMAN
NC score	0.060476 (rank : 5)	θ value	5.27518 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5N5	Gene names	HEMK2, C21orf127, N6AMT1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P).

NC6IP_HUMAN
NC score	0.030027 (rank : 6)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

NC6IP_MOUSE
NC score	0.026902 (rank : 7)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

OSBL7_HUMAN
NC score	0.011328 (rank : 8)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).