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Network neighborhood for query Sequence : BOREA_HUMAN

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BOREA_HUMAN
SwissProt Accessions	Q53HL2, Q53HN1, Q96AM3, Q9NVW5	Gene names	CDCA8, PESCRG3
Domain Architecture	No domain graphic available
Description	Borealin (Dasra-B) (hDasra-B) (Cell division cycle-associated protein 8) (Pluripotent embryonic stem cell-related gene 3 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BOREA_HUMAN
θ value	5.77539e-148 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q53HL2, Q53HN1, Q96AM3, Q9NVW5	Gene names	CDCA8, PESCRG3
Domain Architecture	No domain graphic available
Description	Borealin (Dasra-B) (hDasra-B) (Cell division cycle-associated protein 8) (Pluripotent embryonic stem cell-related gene 3 protein).

BOREA_MOUSE
θ value	3.31004e-111 (rank : 2)	NC score	0.985309 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHX3, Q6NVD3, Q8BHB1, Q8BHQ5, Q8BHQ9, Q9CRN4, Q9CS02, Q9CTF4	Gene names	Cdca8
Domain Architecture	No domain graphic available
Description	Borealin (Cell division cycle-associated protein 8) (MESrg).

PRC1_MOUSE
θ value	0.21417 (rank : 3)	NC score	0.062289 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	382	Shared Neighborhood Hits	8
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

CP135_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.027649 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	1290	Shared Neighborhood Hits	11
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CHD8_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.023526 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CCHCR_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.043360 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

TNAP2_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.054612 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q61333, Q922G1	Gene names	Tnfaip2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

CAC1E_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.012567 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CCD46_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.017672 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCHCR_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.033800 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	932	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

AF9_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.024472 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

BACH_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.021044 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BIRC8_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.013865 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CN021_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.022459 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U38, Q8IVF0, Q8TBS6	Gene names	C14orf21, KIAA2021
Domain Architecture	No domain graphic available
Description	Protein C14orf21.

CP135_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.022273 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGB1_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.014165 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KMHN1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.014513 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	950	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

PPE2_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.010307 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

TLK2_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.002144 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	1044	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

UACA_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.011965 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	1622	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

Hits sorted by NC score

BOREA_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.77539e-148 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q53HL2, Q53HN1, Q96AM3, Q9NVW5	Gene names	CDCA8, PESCRG3
Domain Architecture	No domain graphic available
Description	Borealin (Dasra-B) (hDasra-B) (Cell division cycle-associated protein 8) (Pluripotent embryonic stem cell-related gene 3 protein).

BOREA_MOUSE
NC score	0.985309 (rank : 2)	θ value	3.31004e-111 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHX3, Q6NVD3, Q8BHB1, Q8BHQ5, Q8BHQ9, Q9CRN4, Q9CS02, Q9CTF4	Gene names	Cdca8
Domain Architecture	No domain graphic available
Description	Borealin (Cell division cycle-associated protein 8) (MESrg).

PRC1_MOUSE
NC score	0.062289 (rank : 3)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	382	Shared Neighborhood Hits	8
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

TNAP2_MOUSE
NC score	0.054612 (rank : 4)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q61333, Q922G1	Gene names	Tnfaip2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

CCHCR_HUMAN
NC score	0.043360 (rank : 5)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
NC score	0.033800 (rank : 6)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	932	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CP135_HUMAN
NC score	0.027649 (rank : 7)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	1290	Shared Neighborhood Hits	11
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

AF9_HUMAN
NC score	0.024472 (rank : 8)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CHD8_HUMAN
NC score	0.023526 (rank : 9)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CN021_HUMAN
NC score	0.022459 (rank : 10)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U38, Q8IVF0, Q8TBS6	Gene names	C14orf21, KIAA2021
Domain Architecture	No domain graphic available
Description	Protein C14orf21.

CP135_MOUSE
NC score	0.022273 (rank : 11)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

BACH_HUMAN
NC score	0.021044 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

CCD46_MOUSE
NC score	0.017672 (rank : 13)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	1405	Shared Neighborhood Hits	11
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

KMHN1_HUMAN
NC score	0.014513 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	950	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

GOGB1_HUMAN
NC score	0.014165 (rank : 15)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BIRC8_HUMAN
NC score	0.013865 (rank : 16)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CAC1E_MOUSE
NC score	0.012567 (rank : 17)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

UACA_HUMAN
NC score	0.011965 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	1622	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

PPE2_MOUSE
NC score	0.010307 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

TLK2_HUMAN
NC score	0.002144 (rank : 20)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1044	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).