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Network neighborhood for query Sequence : AQP1_HUMAN

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AQP1_HUMAN
SwissProt Accessions	P29972, Q8TBI5, Q8TDC1	Gene names	AQP1, CHIP28
Domain Architecture
Description	Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) (Urine water channel).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AQP1_HUMAN
θ value	3.06238e-149 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P29972, Q8TBI5, Q8TDC1	Gene names	AQP1, CHIP28
Domain Architecture
Description	Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) (Urine water channel).

AQP1_MOUSE
θ value	1.68428e-139 (rank : 2)	NC score	0.999776 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q02013, Q542P1, Q91VY8	Gene names	Aqp1
Domain Architecture
Description	Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) (Early response protein DER2).

MIP_MOUSE
θ value	3.71096e-62 (rank : 3)	NC score	0.982526 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P51180, O00285, Q3UWJ9, Q8BHA2	Gene names	Mip, Palm
Domain Architecture
Description	Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26).

MIP_HUMAN
θ value	5.35859e-61 (rank : 4)	NC score	0.981874 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	P30301	Gene names	MIP, AQP0
Domain Architecture
Description	Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26).

AQP2_HUMAN
θ value	2.65945e-60 (rank : 5)	NC score	0.980614 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P41181, Q9UD68	Gene names	AQP2
Domain Architecture
Description	Aquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein for renal collecting duct) (ADH water channel) (Collecting duct water channel protein) (WCH-CD).

AQP5_HUMAN
θ value	4.24587e-58 (rank : 6)	NC score	0.979670 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P55064	Gene names	AQP5
Domain Architecture
Description	Aquaporin-5 (AQP-5).

AQP2_MOUSE
θ value	9.45883e-58 (rank : 7)	NC score	0.979111 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P56402, Q8VCG5, Q9R232	Gene names	Aqp2
Domain Architecture
Description	Aquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein for renal collecting duct) (ADH water channel) (Collecting duct water channel protein) (WCH-CD).

AQP5_MOUSE
θ value	1.23536e-57 (rank : 8)	NC score	0.978726 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTY4, Q545H1	Gene names	Aqp5
Domain Architecture
Description	Aquaporin-5 (AQP-5).

AQP4_MOUSE
θ value	1.61343e-57 (rank : 9)	NC score	0.971759 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P55088, P97818, Q61131, Q61132, Q8VHE4, Q8VHE5, Q9EQI3	Gene names	Aqp4
Domain Architecture
Description	Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel) (MIWC).

AQP4_HUMAN
θ value	5.19021e-56 (rank : 10)	NC score	0.971050 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P55087, P78564	Gene names	AQP4
Domain Architecture
Description	Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel) (MIWC).

AQP6_HUMAN
θ value	8.57503e-51 (rank : 11)	NC score	0.973151 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q13520	Gene names	AQP6, AQP2L
Domain Architecture
Description	Aquaporin-6 (AQP-6) (Aquaporin-2-like) (hKID).

AQP6_MOUSE
θ value	1.788e-48 (rank : 12)	NC score	0.970245 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C4A0	Gene names	Aqp6
Domain Architecture
Description	Aquaporin-6 (AQP-6).

AQP8_MOUSE
θ value	9.24701e-21 (rank : 13)	NC score	0.884533 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	P56404, Q91XC2	Gene names	Aqp8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

AQP8_HUMAN
θ value	1.2077e-20 (rank : 14)	NC score	0.884486 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	O94778, Q8IUU3, Q9UIA4	Gene names	AQP8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

AQP3_HUMAN
θ value	3.76295e-14 (rank : 15)	NC score	0.714538 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	21
SwissProt Accessions	Q92482, O00108, Q6FGW6	Gene names	AQP3
Domain Architecture
Description	Aquaporin-3 (AQP-3).

AQP9_HUMAN
θ value	6.41864e-14 (rank : 16)	NC score	0.748405 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	O43315, Q9NP32	Gene names	AQP9, SSC1
Domain Architecture
Description	Aquaporin-9 (AQP-9) (Small solute channel 1).

AQP3_MOUSE
θ value	3.18553e-13 (rank : 17)	NC score	0.711297 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R2N1, Q9JJN8, Q9WTJ3	Gene names	Aqp3
Domain Architecture
Description	Aquaporin-3 (AQP-3).

AQP9_MOUSE
θ value	3.89403e-11 (rank : 18)	NC score	0.730204 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJJ3	Gene names	Aqp9
Domain Architecture
Description	Aquaporin-9 (AQP-9).

AQP10_HUMAN
θ value	1.9326e-10 (rank : 19)	NC score	0.642669 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PS8, Q8NG70	Gene names	AQP10
Domain Architecture
Description	Aquaporin-10 (AQP-10) (Small intestine aquaporin).

AQP7_MOUSE
θ value	1.9326e-10 (rank : 20)	NC score	0.684701 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	O54794, Q8C630	Gene names	Aqp7
Domain Architecture
Description	Aquaporin-7 (AQP-7).

AQP7_HUMAN
θ value	2.52405e-10 (rank : 21)	NC score	0.678428 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	O14520, Q5T5L9, Q8NHM3	Gene names	AQP7, AQP7L, AQP9
Domain Architecture
Description	Aquaporin-7 (AQP-7) (Aquaporin-7-like) (Aquaporin adipose) (AQPap).

AQP12_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.175025 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IXF9	Gene names	AQP12A, AQP12, AQPX2
Domain Architecture
Description	Aquaporin-12A (AQP-12).

AQP11_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.040953 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHH1, Q8JZU1	Gene names	Aqp11
Domain Architecture
Description	Aquaporin-11 (AQP-11).

CYB5B_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.057503 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	O43169, Q96CC3, Q9BT35	Gene names	CYB5B, CYB5M, OMB5
Domain Architecture
Description	Cytochrome b5 type B precursor (Cytochrome b5 outer mitochondrial membrane isoform).

Hits sorted by NC score

AQP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.06238e-149 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P29972, Q8TBI5, Q8TDC1	Gene names	AQP1, CHIP28
Domain Architecture
Description	Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) (Urine water channel).

AQP1_MOUSE
NC score	0.999776 (rank : 2)	θ value	1.68428e-139 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q02013, Q542P1, Q91VY8	Gene names	Aqp1
Domain Architecture
Description	Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) (Early response protein DER2).

MIP_MOUSE
NC score	0.982526 (rank : 3)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P51180, O00285, Q3UWJ9, Q8BHA2	Gene names	Mip, Palm
Domain Architecture
Description	Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26).

MIP_HUMAN
NC score	0.981874 (rank : 4)	θ value	5.35859e-61 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	P30301	Gene names	MIP, AQP0
Domain Architecture
Description	Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26).

AQP2_HUMAN
NC score	0.980614 (rank : 5)	θ value	2.65945e-60 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P41181, Q9UD68	Gene names	AQP2
Domain Architecture
Description	Aquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein for renal collecting duct) (ADH water channel) (Collecting duct water channel protein) (WCH-CD).

AQP5_HUMAN
NC score	0.979670 (rank : 6)	θ value	4.24587e-58 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P55064	Gene names	AQP5
Domain Architecture
Description	Aquaporin-5 (AQP-5).

AQP2_MOUSE
NC score	0.979111 (rank : 7)	θ value	9.45883e-58 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P56402, Q8VCG5, Q9R232	Gene names	Aqp2
Domain Architecture
Description	Aquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein for renal collecting duct) (ADH water channel) (Collecting duct water channel protein) (WCH-CD).

AQP5_MOUSE
NC score	0.978726 (rank : 8)	θ value	1.23536e-57 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTY4, Q545H1	Gene names	Aqp5
Domain Architecture
Description	Aquaporin-5 (AQP-5).

AQP6_HUMAN
NC score	0.973151 (rank : 9)	θ value	8.57503e-51 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q13520	Gene names	AQP6, AQP2L
Domain Architecture
Description	Aquaporin-6 (AQP-6) (Aquaporin-2-like) (hKID).

AQP4_MOUSE
NC score	0.971759 (rank : 10)	θ value	1.61343e-57 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P55088, P97818, Q61131, Q61132, Q8VHE4, Q8VHE5, Q9EQI3	Gene names	Aqp4
Domain Architecture
Description	Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel) (MIWC).

AQP4_HUMAN
NC score	0.971050 (rank : 11)	θ value	5.19021e-56 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P55087, P78564	Gene names	AQP4
Domain Architecture
Description	Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel) (MIWC).

AQP6_MOUSE
NC score	0.970245 (rank : 12)	θ value	1.788e-48 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C4A0	Gene names	Aqp6
Domain Architecture
Description	Aquaporin-6 (AQP-6).

AQP8_MOUSE
NC score	0.884533 (rank : 13)	θ value	9.24701e-21 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	P56404, Q91XC2	Gene names	Aqp8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

AQP8_HUMAN
NC score	0.884486 (rank : 14)	θ value	1.2077e-20 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	O94778, Q8IUU3, Q9UIA4	Gene names	AQP8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

AQP9_HUMAN
NC score	0.748405 (rank : 15)	θ value	6.41864e-14 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	O43315, Q9NP32	Gene names	AQP9, SSC1
Domain Architecture
Description	Aquaporin-9 (AQP-9) (Small solute channel 1).

AQP9_MOUSE
NC score	0.730204 (rank : 16)	θ value	3.89403e-11 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJJ3	Gene names	Aqp9
Domain Architecture
Description	Aquaporin-9 (AQP-9).

AQP3_HUMAN
NC score	0.714538 (rank : 17)	θ value	3.76295e-14 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	21
SwissProt Accessions	Q92482, O00108, Q6FGW6	Gene names	AQP3
Domain Architecture
Description	Aquaporin-3 (AQP-3).

AQP3_MOUSE
NC score	0.711297 (rank : 18)	θ value	3.18553e-13 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R2N1, Q9JJN8, Q9WTJ3	Gene names	Aqp3
Domain Architecture
Description	Aquaporin-3 (AQP-3).

AQP7_MOUSE
NC score	0.684701 (rank : 19)	θ value	1.9326e-10 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	21
SwissProt Accessions	O54794, Q8C630	Gene names	Aqp7
Domain Architecture
Description	Aquaporin-7 (AQP-7).

AQP7_HUMAN
NC score	0.678428 (rank : 20)	θ value	2.52405e-10 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	O14520, Q5T5L9, Q8NHM3	Gene names	AQP7, AQP7L, AQP9
Domain Architecture
Description	Aquaporin-7 (AQP-7) (Aquaporin-7-like) (Aquaporin adipose) (AQPap).

AQP10_HUMAN
NC score	0.642669 (rank : 21)	θ value	1.9326e-10 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PS8, Q8NG70	Gene names	AQP10
Domain Architecture
Description	Aquaporin-10 (AQP-10) (Small intestine aquaporin).

AQP12_HUMAN
NC score	0.175025 (rank : 22)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IXF9	Gene names	AQP12A, AQP12, AQPX2
Domain Architecture
Description	Aquaporin-12A (AQP-12).

CYB5B_HUMAN
NC score	0.057503 (rank : 23)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	O43169, Q96CC3, Q9BT35	Gene names	CYB5B, CYB5M, OMB5
Domain Architecture
Description	Cytochrome b5 type B precursor (Cytochrome b5 outer mitochondrial membrane isoform).

AQP11_MOUSE
NC score	0.040953 (rank : 24)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHH1, Q8JZU1	Gene names	Aqp11
Domain Architecture
Description	Aquaporin-11 (AQP-11).