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Network neighborhood for query Sequence : AL2S4_HUMAN

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AL2S4_HUMAN
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AL2S4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

AL2S4_MOUSE
θ value	5.93515e-169 (rank : 2)	NC score	0.888166 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

RN169_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.077492 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

POP1_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.087961 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

TXND2_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.042308 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	793	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ZC11A_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.075644 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CCD91_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.032515 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	699	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

MBB1A_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.052722 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	665	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

OGFR_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.028372 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	1582	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

POT15_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.026613 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	893	Shared Neighborhood Hits	11
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

M3K4_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.012361 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

NFH_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.032283 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	2247	Shared Neighborhood Hits	23
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EPN3_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.031463 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

M3K4_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.012556 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

SEPT9_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.023325 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

CEP35_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.048312 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	811	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

TTF1_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.093202 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ADA19_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.010598 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

RECQ5_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.027594 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	10
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ANR21_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.023094 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ZN746_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.003701 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ANK2_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.020772 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCD12_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.040537 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUD4, Q8N8I4	Gene names	CCDC12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

CKLF4_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.038751 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJ61, Q8K143	Gene names	Cmtm4, Cklfsf4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

HRX_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.042366 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NKX28_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.009626 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	O70584	Gene names	Nkx2-8, Nkx-2.9, Nkx2-9, Nkx2h
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) (Homeobox protein Nkx-2.9).

AKAP6_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.026661 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	263	Shared Neighborhood Hits	5
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

GTSE1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.033291 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

MYST3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.033878 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RP1_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.021172 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

CDC20_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.012987 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

MOES_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.012638 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	892	Shared Neighborhood Hits	12
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

POLK_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.020061 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

INVS_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.013327 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

MOES_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.012771 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	923	Shared Neighborhood Hits	14
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NOL8_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.019648 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	297	Shared Neighborhood Hits	7
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

SM1L2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.008779 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	918	Shared Neighborhood Hits	7
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TARA_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.016751 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	1626	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRIPC_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.019260 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CDC20_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.011183 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

DEN2A_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.008884 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

LRC27_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.012396 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	710	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

PCLO_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.026077 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	2046	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TCAL5_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.013270 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	806	Shared Neighborhood Hits	13
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CS016_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.052058 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	310	Shared Neighborhood Hits	11
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SRRM1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.059480 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.050905 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	1296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

Hits sorted by NC score

AL2S4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

AL2S4_MOUSE
NC score	0.888166 (rank : 2)	θ value	5.93515e-169 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

TTF1_MOUSE
NC score	0.093202 (rank : 3)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

POP1_HUMAN
NC score	0.087961 (rank : 4)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

RN169_HUMAN
NC score	0.077492 (rank : 5)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

ZC11A_HUMAN
NC score	0.075644 (rank : 6)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

SRRM1_HUMAN
NC score	0.059480 (rank : 7)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MBB1A_HUMAN
NC score	0.052722 (rank : 8)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	665	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CS016_HUMAN
NC score	0.052058 (rank : 9)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	310	Shared Neighborhood Hits	11
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SRRM2_HUMAN
NC score	0.050905 (rank : 10)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	1296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CEP35_HUMAN
NC score	0.048312 (rank : 11)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	811	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

HRX_HUMAN
NC score	0.042366 (rank : 12)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TXND2_HUMAN
NC score	0.042308 (rank : 13)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	793	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CCD12_HUMAN
NC score	0.040537 (rank : 14)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUD4, Q8N8I4	Gene names	CCDC12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

CKLF4_MOUSE
NC score	0.038751 (rank : 15)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJ61, Q8K143	Gene names	Cmtm4, Cklfsf4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

MYST3_HUMAN
NC score	0.033878 (rank : 16)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

GTSE1_HUMAN
NC score	0.033291 (rank : 17)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

CCD91_MOUSE
NC score	0.032515 (rank : 18)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	699	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

NFH_MOUSE
NC score	0.032283 (rank : 19)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	2247	Shared Neighborhood Hits	23
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EPN3_HUMAN
NC score	0.031463 (rank : 20)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

OGFR_HUMAN
NC score	0.028372 (rank : 21)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	1582	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RECQ5_HUMAN
NC score	0.027594 (rank : 22)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	10
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

AKAP6_HUMAN
NC score	0.026661 (rank : 23)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	263	Shared Neighborhood Hits	5
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

POT15_HUMAN
NC score	0.026613 (rank : 24)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	893	Shared Neighborhood Hits	11
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PCLO_HUMAN
NC score	0.026077 (rank : 25)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	2046	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SEPT9_MOUSE
NC score	0.023325 (rank : 26)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

ANR21_HUMAN
NC score	0.023094 (rank : 27)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

RP1_MOUSE
NC score	0.021172 (rank : 28)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

ANK2_HUMAN
NC score	0.020772 (rank : 29)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

POLK_HUMAN
NC score	0.020061 (rank : 30)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

NOL8_HUMAN
NC score	0.019648 (rank : 31)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	297	Shared Neighborhood Hits	7
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

TRIPC_HUMAN
NC score	0.019260 (rank : 32)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

TARA_HUMAN
NC score	0.016751 (rank : 33)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	1626	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

INVS_HUMAN
NC score	0.013327 (rank : 34)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TCAL5_HUMAN
NC score	0.013270 (rank : 35)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	806	Shared Neighborhood Hits	13
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CDC20_MOUSE
NC score	0.012987 (rank : 36)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

MOES_MOUSE
NC score	0.012771 (rank : 37)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	923	Shared Neighborhood Hits	14
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
NC score	0.012638 (rank : 38)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	892	Shared Neighborhood Hits	12
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

M3K4_MOUSE
NC score	0.012556 (rank : 39)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

LRC27_HUMAN
NC score	0.012396 (rank : 40)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	710	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

M3K4_HUMAN
NC score	0.012361 (rank : 41)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

CDC20_HUMAN
NC score	0.011183 (rank : 42)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

ADA19_HUMAN
NC score	0.010598 (rank : 43)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

NKX28_MOUSE
NC score	0.009626 (rank : 44)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	O70584	Gene names	Nkx2-8, Nkx-2.9, Nkx2-9, Nkx2h
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) (Homeobox protein Nkx-2.9).

DEN2A_MOUSE
NC score	0.008884 (rank : 45)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

SM1L2_MOUSE
NC score	0.008779 (rank : 46)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	918	Shared Neighborhood Hits	7
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

ZN746_MOUSE
NC score	0.003701 (rank : 47)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.