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Network neighborhood for query Sequence : AATC_HUMAN

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AATC_HUMAN
SwissProt Accessions	P17174	Gene names	GOT1
Domain Architecture
Description	Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AATC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P17174	Gene names	GOT1
Domain Architecture
Description	Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).

AATC_MOUSE
θ value	0 (rank : 2)	NC score	0.998574 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P05201	Gene names	Got1
Domain Architecture
Description	Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).

AATM_HUMAN
θ value	2.00813e-108 (rank : 3)	NC score	0.968529 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

AATM_MOUSE
θ value	2.00813e-108 (rank : 4)	NC score	0.968098 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

LMAN1_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.060019 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

VPS16_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.037721 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q920Q4, Q8R3C3, Q99KZ4	Gene names	Vps16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (mVPS16).

LMAN1_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.042608 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

K2C3_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.003167 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	443	Shared Neighborhood Hits	2
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

VPS16_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.032821 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H269, Q5JUB1, Q8WU31, Q96EE7, Q96N92, Q9H1Q4, Q9H1Q5	Gene names	VPS16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (hVPS16).

SRBP1_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.011013 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

LGMN_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.012203 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O89017	Gene names	Lgmn, Prsc1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

PPE2_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.007063 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

Hits sorted by NC score

AATC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P17174	Gene names	GOT1
Domain Architecture
Description	Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).

AATC_MOUSE
NC score	0.998574 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P05201	Gene names	Got1
Domain Architecture
Description	Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).

AATM_HUMAN
NC score	0.968529 (rank : 3)	θ value	2.00813e-108 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

AATM_MOUSE
NC score	0.968098 (rank : 4)	θ value	2.00813e-108 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

LMAN1_MOUSE
NC score	0.060019 (rank : 5)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

LMAN1_HUMAN
NC score	0.042608 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

VPS16_MOUSE
NC score	0.037721 (rank : 7)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q920Q4, Q8R3C3, Q99KZ4	Gene names	Vps16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (mVPS16).

VPS16_HUMAN
NC score	0.032821 (rank : 8)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H269, Q5JUB1, Q8WU31, Q96EE7, Q96N92, Q9H1Q4, Q9H1Q5	Gene names	VPS16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (hVPS16).

LGMN_MOUSE
NC score	0.012203 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O89017	Gene names	Lgmn, Prsc1
Domain Architecture
Description	Legumain precursor (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1).

SRBP1_HUMAN
NC score	0.011013 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PPE2_MOUSE
NC score	0.007063 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

K2C3_HUMAN
NC score	0.003167 (rank : 12)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	443	Shared Neighborhood Hits	2
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).