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Network neighborhood for query Sequence : AADAT_HUMAN

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AADAT_HUMAN
SwissProt Accessions	Q8N5Z0, Q9UL02	Gene names	AADAT, KAT2
Domain Architecture
Description	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39) (2- aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AADAT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5Z0, Q9UL02	Gene names	AADAT, KAT2
Domain Architecture
Description	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39) (2- aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT).

AADAT_MOUSE
θ value	0 (rank : 2)	NC score	0.994129 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM8	Gene names	Aadat, Kat2
Domain Architecture
Description	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39) (2- aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT).

KAT1_MOUSE
θ value	4.92598e-06 (rank : 3)	NC score	0.371157 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTY1, Q8BY27	Gene names	Ccbl1, Kat
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

KAT1_HUMAN
θ value	4.1701e-05 (rank : 4)	NC score	0.351949 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q16773, Q8N191	Gene names	CCBL1
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

ATTY_HUMAN
θ value	0.000270298 (rank : 5)	NC score	0.268412 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P17735	Gene names	TAT
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

ATTY_MOUSE
θ value	0.00102713 (rank : 6)	NC score	0.252485 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

SIA8E_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.029749 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O15466	Gene names	ST8SIA5, SIAT8E
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

UCR6_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.039038 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P14927	Gene names	UQCRB, UQBP
Domain Architecture
Description	Ubiquinol-cytochrome c reductase complex 14 kDa protein (EC 1.10.2.2) (Complex III subunit VI) (QP-C).

RIPK1_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.006701 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

Hits sorted by NC score

AADAT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5Z0, Q9UL02	Gene names	AADAT, KAT2
Domain Architecture
Description	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39) (2- aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT).

AADAT_MOUSE
NC score	0.994129 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM8	Gene names	Aadat, Kat2
Domain Architecture
Description	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39) (2- aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT).

KAT1_MOUSE
NC score	0.371157 (rank : 3)	θ value	4.92598e-06 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTY1, Q8BY27	Gene names	Ccbl1, Kat
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

KAT1_HUMAN
NC score	0.351949 (rank : 4)	θ value	4.1701e-05 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q16773, Q8N191	Gene names	CCBL1
Domain Architecture
Description	Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Kynurenine-- oxoglutarate transaminase I) (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13).

ATTY_HUMAN
NC score	0.268412 (rank : 5)	θ value	0.000270298 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P17735	Gene names	TAT
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

ATTY_MOUSE
NC score	0.252485 (rank : 6)	θ value	0.00102713 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZR1, Q3UER7, Q8BTI1	Gene names	Tat
Domain Architecture
Description	Tyrosine aminotransferase (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase) (TAT).

UCR6_HUMAN
NC score	0.039038 (rank : 7)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P14927	Gene names	UQCRB, UQBP
Domain Architecture
Description	Ubiquinol-cytochrome c reductase complex 14 kDa protein (EC 1.10.2.2) (Complex III subunit VI) (QP-C).

SIA8E_HUMAN
NC score	0.029749 (rank : 8)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O15466	Gene names	ST8SIA5, SIAT8E
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

RIPK1_MOUSE
NC score	0.006701 (rank : 10)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).